A customized protocol to assess bone quality in the metacarpal head, metacarpal shaft and distal radius: a high resolution peripheral quantitative computed tomography precision study

Table 3 Summary of results for the Metacarpal Head (MH) 2 & 3 regions of interest (n = 10)

Variables				Mean (SD)		ICC (0.000-1.000)		Mean coefficient of variation (CV%)		Root mean square CV (RMSCV%)		Least significant change% (LSC%95)
Variables				MH3	MH2	MH3	MH2	MH3	MH2	MH3	MH2	MH3	MH2
Density (Apparent)	Full bone (mgHA/cm3)	vBMD_full	D & S	438 (89)	434 (82)	0.997	0.998	0.83	0.57	1.0	0.78	2.8	2.2
	Cortical (mgHA/cm3)	vBMD_cort	D	743 (106)	751 (101)	0.975	0.975	1.5	1.3	2.1	1.6	6.0	4.5
	Trabecular (mgHA/cm3)	vBMD_trab	D & S	387 (79)	378 (73)	0.996	0.997	0.8	0.7	1.2	1.0	3.2	2.9
Cortical bone	Thickness (mm)	CtTh	D	0.39 (0.07)	0.39 (0.06)	0.933	0.973	4.8	1.6	6.17	2.7	17.1	7.4
Cortical bone	Porosity (%)	CtPo	D	1.2 (0.7)	1.2 (0.4)	0.153	0.727	23.2	17.0	33.2	22.2	92.1	61.4
Trabecular bone	Volume fraction (%)	BV/TV_trab	D	46 (5)	46 (6)	0.984	0.984	1.2	1.3	1.5	1.6	4.3	4.5
	Volume fraction (%)	BV/TV_trabs	S	26 (13)	26 (13)	0.984	0.984	1.2	1.3	1.5	1.6	4.3	4.5
	Number (1/mm)	TbN	D & S	2.6 (0.24)	2.5 (0.23)	0.904	0.884	2.1	2.2	2.5	2.8	6.9	7.7
	Thickness (mm)	TbTh	D	0.23 (0.02)	0.24 (0.02)	0.978	0.978	0.74	1.1	3.9	3.5	10.8	9.8
	Thickness (mm)	TbTh_s	S	0.11 (0.03)	0.11 (0.03)	0.978	0.978	0.74	1.1	3.9	3.5	10.8	9.8
	Separation (mm)	TbSp	D	0.34 (0.05)	0.34 (0.06)	0.928	0.944	3.0	3.0	1.1	1.3	3.0	3.5
	Separation (mm)	TbSp_s	S	0.27 (0.05)	0.29 (0.05)	0.928	0.944	3.0	3.0	1.1	1.3	3.0	3.5

D = Direct Transformation Method; S (Grey fill) = Derived Standard Clinical Equivalent.

ISSN: 1471-2474