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Table 3 Relationship between creatinine clearance bands and the presence of tophi: logistic regression analysis

From: Reduced creatinine clearance is associated with early development of subcutaneous tophi in people with gout

Creatinine clearance (ml/min)

No tophi (n = 243), n (%)

Tophi (n = 47), n (%)

Unadjusted odds ratio (95% CI)

Unadjusted P

Multivariate* adjusted odds ratio (95% CI)

Multivariate* adjusted P

>90

63 (25.9%)

4 (9%)

1.0 (ref)

-

1.0 (ref)

-

>60-90

90 (37.0%)

14 (30%)

2.4 (0.8-7.8)

0.13

2.2 (0.7-7.3)

0.19

>30-60

74 (30.5%)

19 (40%)

4.1 (1.3-12.7)

0.015

3.0 (0.9-10.0)

0.07

0-30

16 (6.6%)

10 (21%)

9.7 (2.7-35.0)

0.001

7.0 (1.8-27.6)

0.005

  1. *adjusted for ethnicity, corticosteroid use, diuretic use and colchicine use.