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Table 2 Expression levels of candidate genes on the microarray and in the qPCR confirmation study

From: Expression profiling in spondyloarthropathy synovial biopsies highlights changes in expression of inflammatory genes in conjunction with tissue remodelling genes

Array data Norm-OA (9)   AS-SpA (6)   AS-SpA/Norm-OA p-value
MMP3 480.66   2260.32   4.7 0.005255
MMP1 199.47   701.47   3.51 0.001053
DKK3 517.49   190.98   -2.71 0.003263
KREMEN1 988.68   674.73   -1.46 6.50E-03
PTGER4 317.58   393.08   1.24 4.70E-02
qPCR Norm-OA (9) SD AS-SpA (7) SD AS-SpA/Norm-OA p-value
MMP3 0.00026 0.00058 0.00295 0.00412 11.35 0.07
DKK3 0.101 0.073 0.037 0.061 -2.7 0.086
PTGER4 66.6 62.9 126.7 50.1 1.9 0.042
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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