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Table 2 Expression levels of candidate genes on the microarray and in the qPCR confirmation study

From: Expression profiling in spondyloarthropathy synovial biopsies highlights changes in expression of inflammatory genes in conjunction with tissue remodelling genes

Array data

Norm-OA (9)

 

AS-SpA (6)

 

AS-SpA/Norm-OA

p-value

MMP3

480.66

 

2260.32

 

4.7

0.005255

MMP1

199.47

 

701.47

 

3.51

0.001053

DKK3

517.49

 

190.98

 

-2.71

0.003263

KREMEN1

988.68

 

674.73

 

-1.46

6.50E-03

PTGER4

317.58

 

393.08

 

1.24

4.70E-02

qPCR

Norm-OA (9)

SD

AS-SpA (7)

SD

AS-SpA/Norm-OA

p-value

MMP3

0.00026

0.00058

0.00295

0.00412

11.35

0.07

DKK3

0.101

0.073

0.037

0.061

-2.7

0.086

PTGER4

66.6

62.9

126.7

50.1

1.9

0.042

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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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