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Table 4 The ten mammalian proteins found most frequently in rules for each of the three classes, not including the default control class, from the emPAI dataset

From: Analysis of mass spectrometry data from the secretome of an explant model of articular cartilage exposed to pro-inflammatory and anti-inflammatory stimuli using machine learning

IL-1β

Carprofen

IL-1β and Carprofen

Triosephosphate isomerase (73.4)

Alpha-2-HS-glycoprotein (99.3)

interleukin 8 (81.4)

Albumin (40.4)

Tumor necrosis factor receptor superfamily member 11B (15.6)

Lumican (14.9)

Serum amyloid A protein (23)

Pseudouridylate synthase 7 homolog (15.1)

Matrix metalloproteinase 3 (3.1)

Matrix metalloproteinase 3 (21.3)

Lysozyme C (2)

Desmin (2.6)

Vimentin-1 (9.8)

Apolipoprotein E (1.8)

Clusterin (2)

Vimentin (6)

Matrix gla protein (1.8)

Syndecan-4 (1.4)

Enolase B (5.9)

Fibromodulin (1.4)

Ribonuclease 4 (1)

Thrombospondin 1(5.3)

Clusterin (1.3)

Thrombospondin-3 (0.8)

Enolase A (3.4)

Metalloproteinase inhibitor 1 (0.6)

Enolase (0.6)

Keratin (3.8)

Retinoblastoma-like protein 2 (0.4)

Cartilage intermediate layer protein 1 (0.4)

  1. The percentage of rules each protein was used in is shown in brackets.