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Table 3 The ten mammalian proteins found most frequently in rules for each of the three classes, not including the default control class, from the ProteinProphet dataset

From: Analysis of mass spectrometry data from the secretome of an explant model of articular cartilage exposed to pro-inflammatory and anti-inflammatory stimuli using machine learning

IL-1β

Carprofen

IL-1β and Carprofen

Matrix metalloproteinase 3 (47.5)

Matrix gla protein (52.5)

interleukin 8 (93.1)

Triosephosphate isomerase (19.6)

Apolipoprotein E (44.8)

Matrix metalloproteinase 3 (6.87)

Enolase (4.56)

Hyaluronan and proteoglycan link protein 1 (22.7)

Pyruvate kinase isozyme M1 (5.59)

interleukin 8 (2.61)

Target of Nesh-SH3 (5.24)

Protein S100-A1 (5.39)

Leukocyte antigen CD37 (2.58)

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (5.1)

Bardet-Biedl syndrome 10 protein (5.35)

Fibromodulin (2.58)

Extracellular matrix protein 1 (4.84)

50S ribosomal protein L29 (5.26)

Hyaluronan and proteoglycan link protein 1 (1.79)

Alpha-1-antitrypsin (2.89)

Max-like protein X (5.08)

Cartilage intermediate layer protein 1 (1.32)

Keratin (2.82)

Trypsin (4.82)

Metalloproteinase inhibitor 1 (1.22)

Decorin (2.59)

Triosephosphate isomerase (4.74)

Thrombospondin 1(1.13)

Myotubularin-related protein 1 (2.54)

Alpha-2-HS-glycoprotein (4.62)

  1. The percentage of rules each protein was used in is shown in brackets.