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Table 3 The ten mammalian proteins found most frequently in rules for each of the three classes, not including the default control class, from the ProteinProphet dataset

From: Analysis of mass spectrometry data from the secretome of an explant model of articular cartilage exposed to pro-inflammatory and anti-inflammatory stimuli using machine learning

IL-1β Carprofen IL-1β and Carprofen
Matrix metalloproteinase 3 (47.5) Matrix gla protein (52.5) interleukin 8 (93.1)
Triosephosphate isomerase (19.6) Apolipoprotein E (44.8) Matrix metalloproteinase 3 (6.87)
Enolase (4.56) Hyaluronan and proteoglycan link protein 1 (22.7) Pyruvate kinase isozyme M1 (5.59)
interleukin 8 (2.61) Target of Nesh-SH3 (5.24) Protein S100-A1 (5.39)
Leukocyte antigen CD37 (2.58) Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (5.1) Bardet-Biedl syndrome 10 protein (5.35)
Fibromodulin (2.58) Extracellular matrix protein 1 (4.84) 50S ribosomal protein L29 (5.26)
Hyaluronan and proteoglycan link protein 1 (1.79) Alpha-1-antitrypsin (2.89) Max-like protein X (5.08)
Cartilage intermediate layer protein 1 (1.32) Keratin (2.82) Trypsin (4.82)
Metalloproteinase inhibitor 1 (1.22) Decorin (2.59) Triosephosphate isomerase (4.74)
Thrombospondin 1(1.13) Myotubularin-related protein 1 (2.54) Alpha-2-HS-glycoprotein (4.62)
  1. The percentage of rules each protein was used in is shown in brackets.