|
Model 1aRR (95% CI)
|
Model 2aRR (95% CI)
|
Model 3bRR (95% CI)
|
Model 4bRR (95% CI)
|
---|
Risk factor
| | | | |
---|
Male sex
|
1.73 (1.36, 2.21)
|
1.10 (0.85, 1.43)
|
1.02 (0.80, 1.31)
|
1.54 (1.21, 1.97)
|
African American race
|
1.79 (1.37, 2.33)
|
1.68 (1.29, 2.18)
|
1.50 (1.15, 1.94)
|
1.64 (1.26, 2.13)
|
<High school education
|
1.27 (0.99, 1.63)
|
1.29 (1.00, 1.65)
|
1.15 (0.89, 1.49)
|
1.23 (0.96, 1.58)
|
Hypertension
|
1.65 (1.3, 2.09)
|
1.47 (1.15, 1.87)
|
1.27 (0.99, 1.62)
|
1.44 (1.12, 1.84)
|
Coronary heart disease
|
1.57 (0.99, 2.50)
|
1.60 (1.00, 2.56)
|
1.48 (0.90, 2.43)
|
1.45 (0.89, 2.37)
|
Smoking status
| | | | |
Current smoker
|
1.27 (0.97, 1.67)
|
1.29 (0.98, 1.69)
|
1.26 (0.96, 1.66)
|
1.27 (0.96, 1.66)
|
Former smoker
|
0.84 (0.64, 1.11)
|
0.81 (0.62, 1.07)
|
0.78 (0.60, 1.03)
|
0.83 (0.63, 1.09)
|
Never smoker
|
Reference
|
Reference
|
Reference
|
Reference
|
Body mass index, kg/m
2
| | | | |
BMI ≥ 35
|
3.47 (2.33, 5.18)
|
2.07 (1.37, 3.14)
|
2.18 (1.44, 3.31)
|
3.25 (2.16, 4.9)
|
30 ≤ BMI < 35
|
2.37 (1.65, 3.41)
|
1.76 (1.22, 2.54)
|
1.90 (1.31, 2.75)
|
2.37 (1.64, 3.40)
|
25 ≤ BMI < 30
|
2.01 (1.46, 2.78)
|
1.64 (1.19, 2.26)
|
1.79 (1.30, 2.46)
|
2.04 (1.48, 2.81)
|
BMI < 25
|
Reference
|
Reference
|
Reference
|
Reference
|
eGFR, ml/min/1.73 m
2
| | | | |
<60
|
2.85 (1.62, 5.01)
|
1.97 (1.12, 3.47)
|
2.05 (1.24, 3.39)
|
2.86 (1.70, 4.82)
|
60-90
|
1.12 (0.89, 1.42)
|
0.95 (0.75, 1.20)
|
1.05 (0.84, 1.32)
|
1.18 (0.94, 1.48)
|
≥ 90
|
Reference
|
Reference
|
Reference
|
Reference
|
Triglyceride, mg/dL
| | | | |
Quartile 4: ≥ 157
|
2.00 (1.38, 2.89)
|
1.48 (1.03, 2.13)
|
1.44 (1.01, 2.04)
|
1.93 (1.35, 2.76)
|
Quartile 3: 110 -156
|
1.46 (1.01, 2.12)
|
1.20 (0.83, 1.73)
|
1.12 (0.79, 1.60)
|
1.41 (0.99, 2.02)
|
Quartile 2: 79 - 109
|
1.08 (0.73, 1.60)
|
0.96 (0.65, 1.41)
|
1.00 (0.68, 1.46)
|
1.12 (0.76, 1.65)
|
Quartile 1: ≤ 78
|
Reference
|
Reference
|
Reference
|
Reference
|
Serum Urate Level at Visit1, mg/dL
| |
2.33 (1.94, 2.80)
| | |
Serum Urate Level at Visit2, mg/dL
| | |
1.92 (1.78, 2.07)
| |
Change in serum urate level (Visit 2-Visit 1), mg/dL
| | | |
1.60 (1.47, 1.74)
|
-
aThe number of participants included in analysis was 8,342.
-
bThe number of participants included in analysis was 8,211.
- Note: Relative risks and 95% confidence intervals are reported. Each model includes all the risk factors with relative risks and 95% confidence intervals listed in the column. Hyperuricemia was defined as serum urate levels greater than 7.0 mg/dL.