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Table 1 Effect of 10 days' ALN treatment on DFBMD in growing rabbits

From: Cathepsin K inhibitors increase distal femoral bone mineral density in rapidly growing rabbits

ALN dose (μg/kg) DFBMD (mg/cm2) % BMD gain
  Veh ALN  
50 241.4 ± 9.2 277.8 ± 8.4** 15
100 270.5 ± 7.9 313.7 ± 3.9*** 16
200 242.0 ± 3.4 281.7 ± 6.4*** 16
500 241.6 ± 5.2 291.2 ± 9.4*** 21
  1. Mean ± standard error of the mean; **p < 0.01, ***p < 0.001 vs. vehicle.
  2. ALN = alendronate, DFBMD = distal femoral bone mineral density, Veh = vehicle.