Efficacy of low-dose intra-articular tranexamic acid in total knee replacement; a prospective triple-blinded randomized controlled trial

Table 2 Blood loos and blood transfusion outcome in all three groups

	Control group	TXA 250 mg	TXA 500 mg	p-value
	(n = 45)	(n = 45)	(n = 45)
Blood loss outcome variables
Drainage blood loss✝ (ml)	546.9 (273.0)	475.0 (254.4)	430.2 (224.0)	0.09
Total hemoglobin loss✝ (g/dl)	2.9 (1.2)	2.2 (0.7)**^a	2.2 (0.7)**^b	< 0.001**
Calculated total blood loss✝ (ml)	329.2 (119.4)	239.7 (83.7)**^a	217.2 (86.1)**^b	< 0.001**
Packed red blood-cell transfusion
Blood transfusion use◆	10 (22%)	6 (13%)	0 (0%)**	0.005*

✝ = The values were presented as mean (standard deviation); *, p < 0.05; **, p < 0.001.
◆ = The values were presented as number of patients having that condition (percentage of this group).
a = comparison between control and TXA-250 group with p < 0.05.
b = comparison between control and TXA-500 group with p < 0.05.

ISSN: 1471-2474