Figure 2From: Efficacy of low-dose intra-articular tranexamic acid in total knee replacement; a prospective triple-blinded randomized controlled trial The mean accumulated drainage volume (ADV) at each time point throughout 48-hour drainage recorded period, in all three groups, demonstrated a significant reduction in both TXA groups only the early period after clamp release (the first 12-hour period in TXA-250 group and the first 20-hour period in TXA-500 group) (ā ā=āpā<ā0.05). Back to article page