Variable | Strata | Men | Women | ||||
---|---|---|---|---|---|---|---|
 |  | N | Hazard ratio (95% CI) | p-value | N | Hazard ratio (95% CI) | p-value |
Age | <20.0 years | 1080 | 1.00 | Referent | 325 | 1.00 | Referent |
20.0-24.9 years | 623 | 1.21 (1.04-1.46) | 0.01 | 195 | 1.25 (1.00-1.55) | 0.05 | |
25.0-29.9 years | 90 | 1.25 (0.87-1.78) | 0.23 | 23 | 1.21 (0.72-2.05) | 0.47 | |
≥30.0 years | 38 | 2.17 (1.41-3.33) | <0.01 | 10 | 2.99 (1.47-6.07) | <0.01 | |
Body Mass Index | <25.0 kg/m2 | 1048 | 1.00 | Referent | 401 | 1.00 | Referent |
25.0-29.9 kg/m2 | 658 | 1.13 (0.96-1.33) | 0.15 | 145 | 0.91 (0.72-1.15) | 0.42 | |
≥30 kg/m2 | 132 | 1.05 (0.77-1.43) | 0.77 | 5 | 0.96 (0.31-3.01) | 0.95 | |
Smoked ≥100 Cigarettes in Life | No | 1273 | 1.00 | Referent | 404 | 1.00 | Referent |
Yes | 563 | 1.37 (1.17-1.61) | <0.01 | 149 | 1.28 (1.00-1.60) | 0.05 | |
Age Started Smoking | Never | 932 | 1.00 | Referent | 316 | 1.00 | Referent |
<13 years | 72 | 1.54 (1.07-2.23) | 0.02 | 19 | 1.37 (0.78-2.40) | 0.27 | |
13-16 years | 520 | 1.18 (0.99-1.42) | 0.07 | 134 | 1.05 (0.82-1.34) | 0.72 | |
≥17 years | 314 | 1.05 (0.83-1.31) | 0.69 | 84 | 1.09 (0.81-1.46) | 0.57 | |
Days Smoked in 30 Days Before OSUT | None | 1368 | 1.00 | Referent | 425 | 1.00 | Referent |
1-9 days | 107 | 1.09 (0.77-1.53) | 0.63 | 28 | 1.25 (0.79-1.96) | 0.34 | |
10-19 days | 74 | 1.13 (0.76-1.66) | 0.55 | 15 | 0.85 (0.44-1.66) | 0.64 | |
≥20 days | 298 | 1.45 (1.19-1.77) | <0.01 | 85 | 1.20 (0.91-1.58) | 0.20 | |
Cigarettes Smoked in 30 Days Before OSUT | None | 1375 | 1.00 | Referent | 425 | 1.00 | Referent |
1-9 cigarettes/day | 270 | 1.29 (1.04-1.59) | 0.02 | 80 | 1.11 (0.84-1.48) | 0.46 | |
10-19 cigarettes/day | 126 | 1.23 (0.91-1.67) | 0.17 | 31 | 1.12 (0.71-1.77) | 0.61 | |
≥20 cigarettes/day | 66 | 1.76 (1.23-2.52) | <0.01 | 17 | 1.51 (0.88-2.59) | 0.13 | |
Used Smokeless Tobacco 30 Days Before OSUT | No | 1473 | 1.00 | Referent | 536 | 1.00 | Referent |
Yes | 365 | 1.00 (0.82-1.21) | 0.96 | 17 | 0.80 (0.44-1.45) | 0.46 | |
Physical Activity Before OSUT Compared to Peers | Much less active | 91 | 1.52 (1.06-2.17) | 0.02 | 62 | 1.25 (0.81-1.93) | 0.32 |
Less active | 315 | 1.53 (1.20-1.96) | <0.01 | 128 | 1.14 (0.78-1.67) | 0.49 | |
Average | 441 | 1.08 (0.85-1.38) | 0.53 | 146 | 0.90 (0.62-1.31) | 0.58 | |
More active | 637 | 0.85 (0.67-1.08) | 0.18 | 161 | 0.84 (0.57-1.22) | 0.35 | |
Much more active | 354 | 1.00 | Referent | 56 | 1.00 | Referent | |
Exercise or Sports Frequency 2 Months Before OSUT | ≤1 time/week | 281 | 1.42 (1.12-1.80) | <0.01 | 90 | 1.39 (1.02-1.91) | 0.04 |
2-4 time/week | 912 | 0.97 (0.82-1.15) | 0.70 | 310 | 1.13 (0.88-1.44) | 0.34 | |
≥5 time/week | 707 | 1.00 | Referent | 153 | 1.00 | Referent | |
Time Running/Jogging before OSUT | ≤1 month | 451 | 1.38 (1.08-1.68) | <0.01 | 143 | 1.66 (1.18-2.32) | <0.01 |
2-6 months | 949 | 1.06 (0.87-1.30) | 0.09 | 308 | 1.63 (1.20-2.21) | <0.01 | |
≥7 months | 437 | 1.00 | Referent | 102 | 1.00 | Referent | |
Time Weight Training before OSUT | ≤1 month | 660 | 1.25 (1.04-1.51) | <0.01 | 274 | 1.47 (1.08-2.01) | 0.02 |
2-6 months | 537 | 1.12 (0.91-1.36) | 0.11 | 190 | 1.33 (0.95-1.86) | 0.09 | |
≥7 months | 640 | 1.00 | Referent | 88 | 1.00 | Referent | |
Prior Lower Limb Injury | No | 1327 | 1.00 | Referent | 406 | 1.00 | Referent |
Yes | 510 | 1.19 (1.01-1.41) | 0.04 | 147 | 1.08 (0.85-1.35) | 0.54 | |
Prior Injury Prevent Activities ≥1 Week | No prior injury | 1327 | 1.00 | Referent | 406 | 1.00 | Referent |
No | 171 | 1.12 (0.92-1.38) | 0.26 | 45 | 1.07 (0.72-1.58) | 0.38 | |
Yes | 337 | 1.29 (1.00-1.67) | 0.05 | 102 | 1.22 (0.79-1.88) | 0.75 | |
Totally Recovered from Prior Injury | No prior injury | 1325 | 1.00 | Referent | 406 | 1.00 | Referent |
No | 27 | 2.07 (1.22-3.52) | <0.01 | 11 | 1.50 (0.77-2.92) | 0.23 | |
Yes | 481 | 1.15 (0.97-1.37) | 0.11 | 136 | 1.05 (0.82-1.33) | 0.71 | |
Age at Menarche | No menses yet | Â | 4 | 0.23 (0.03-1.67) | 0.15 | ||
6-10 years | 48 | 1.21 (0.85-1.72) | 0.29 | ||||
11-14 years | 437 | 1.00 | Referent | ||||
15-17 years | 64 | 0.78 (0.56-1.10) | 0.16 | ||||
Gone ≥6 Months without Menstrual Cycle in Last Year | No | 494 | 1.00 | Referent | |||
Yes | 44 | 1.60 (1.13-2.26) | <0.01 | ||||
No menses yet | 4 | 0.25 (0.04-1.76) | 0.16 | ||||
Taken Birth Control Pills in Last 12 Months | No | 299 | 1.00 | Referent | |||
Yes | 249 | 1.11 (0.90-1.36) | 0.33 | ||||
Ever Pregnant | No | 494 | 1.00 | Referent | |||
Yes | 59 | 1.41 (1.02-1.94) | 0.04 |