Maximum reflexive grip strength and palmar mechanical sensation in the preferred reach limb, examined after performing either a LRLF, HRLF, LRHF and HRHF task for 12 weeks. (A & B) Maximum reflexive grip strength in grams (g) in week 0 and week 12. (C & D) Palmar mechanical sensation, tested as withdrawal thresholds to mechanical stimulation with a series of von Frey hairs, in week 0 and week 12. Symbols: a and aa: p < 0.05 and p < 0.01, compared to LRLF rats; **: p < 0.01, compared to normal controls rat data combined with NC/naïve data (indicated by dashed line). Mean and SEM are shown.