Inflammatory cytokines levels in radial and ulnar bones, and first row of carpal bones, tested using ELISA in week 0 (immediately following the training period) or after performing either a LRLF, HRLF, LRHF and HRHF task for 12 weeks. (A & D) Bone TNFalpha in week 0 and 12. (B & E) Bone IL-1beta in week 0 and 12. (C & F) Bone IL-1alpha in week 0 and 12. Symbols: a and aa: p < 0.05 and p < 0.01, compared to LRLF rats; b and bb: p < 0.05 and p < 0.01, compared to HRLF rats; * and **: p < 0.05 and p < 0.01, compared to food restricted controls (FRC) rats (indicated by dashed line). Mean and SEM are shown.