The association of body-mass index and depressed mood with knee pain and activity limitations in knee osteoarthritis: results from the Amsterdam osteoarthritis cohort

Table 3 Association of BMI and depressed mood with self-reported activity limitations

Analysis	Independent variables	B (95% CI)	β	p	Semi-partial r²× 100%
1.	BMI	0.77 (0.21, 1.03)	0.33	<0.001	10.9%
2.	HADS depression	0.83 (0.37, 1.29)	0.21	<0.001	4.2%
3.	BMI	0.70 (0.44, 0.96)	0.30	<0.001	8.7%
3.	HADS depression	0.59 (0.14, 1.04)	0.15	0.011	2.0%
	Dominance analysis
	Overall average BMI	(0.109 + 0.087)/2 = 0.098			9.8%
	Overall average HADS depression	(0.042 + 0.020)/2 = 0.031			3.1%

Self-reported activity limitations were measured with the physical function subscale of the Western Ontario and McMaster Universities Osteoarthritis Index. In all analyses we adjusted for age, gender, marital status, education level, radiographic OA and comorbidity. B (95% CI), Regression coefficient ( 95% confidence interval). β, Standardized regression coefficient. Semi-partial r² = squared semi-partial correlation coefficient. BMI, Body-mass index. HADS, Hospital Anxiety and Depression Scale.

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