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Figure 5 | BMC Musculoskeletal Disorders

Figure 5

From: An ultrasound study of altered hydration behaviour of proteoglycan-degraded articular cartilage

Figure 5

Histological sections stained with Safranin O and fast green. (A) Histological section of normal cartilage indicating smooth surface, the well-arranged cartilage cells in a rule, no erosion, ulcers or fissures in the cartilage tissue, and the uniform staining with Safranin O red. (B) Histological section of PG-degraded cartilage indicating less smooth surface in comparison with normal cartilage in (A), the destructed local chondrocytes in the cartilage forming a cavity (arrows), moderate reduction of Safranin O staining indicating a degeneration of proteoglycans in the cartilage matrix. (× 100).

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