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Table 3 Distribution of clinical index based on femoral neck (FN), total hip (TH), or lumbar spine BMDs in routine screening group

From: Validation of an osteoporosis self-assessment tool to identify primary osteoporosis and new osteoporotic vertebral fractures in postmenopausal Chinese women in Beijing

Group OSTA value FN, TH, or L1–4 BMD Total Sensitivity Specificity PPV NPV
T ≤ -2.5 T > -2.5 % 95% CI % 95% CI % 95% CI % 95% CI
Routinely screened, all ages High risk (≤ -1) 151 196 347 65.9 59.4–72.1 75.5 72.3–78.4 43.5 38.2–48.9 88.5 85.9–90.8
Low risk (> -1) 78 603 681
  Total 229 799 1028         
< 60 years High risk (≤ -1) 20 43 63 29.9 19.3–42.3 91.1 88.2–93.5 31.7 20.6–44.7 90.3 87.4–92.8
  Low risk (> -1) 47 44 487
  Total 67 483 550        
60–69 years High risk (≤ -1) 52 75 127 68.4 56.7–78.6 64.6 57.8–71.0 69.3 57.6–79.5 85.1 78.6–90.2
  Low risk (> -1) 24 137 161
  Total 76 212 288         
≥ 70 years High risk (≤ -1) 79 78 157 91.9 83.9–96.7 25.0 17.0–34.4 50.3 42.2–58.4 78.8 61.1–91.0
  Low risk (> -1) 7 26 33
  Total 86 104 190         
  1. PPV positive predictive value, NPV negative predictive value.