Figure 7From: Subchondral pre-solidified chitosan/blood implants elicit reproducible early osteochondral wound-repair responses including neutrophil and stromal cell chemotaxis, bone resorption and repair, enhanced repair tissue integration and delayed matrix deposition Distribution of repair tissues in treated defects and volume density of neutrophils and stromal cells. Relative cross-sectional area of apoptotic, neutrophil-rich, neutrophil+stromal and stromal tissues in sections collected (A) at the edge and (B) through the middle of treated defects in collagen type I-stained cryosections (N=4). Apoptotic tissues cover a larger area in the middle of 150K-treated defects after 21 days than 40K and 10K-treated defects (p=0.0417, p=0.0515, respectively). (C) Volume density (Vv) of neutrophils and stromal cells in 40x magnification pictures of neutrophil-rich, neutrophil+stromal and stromal tissues in the middle of day 21 treated defects of collagen type I-stained cryosections (N=4).Back to article page