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Figure 7 | BMC Musculoskeletal Disorders

Figure 7

From: Subchondral pre-solidified chitosan/blood implants elicit reproducible early osteochondral wound-repair responses including neutrophil and stromal cell chemotaxis, bone resorption and repair, enhanced repair tissue integration and delayed matrix deposition

Figure 7

Distribution of repair tissues in treated defects and volume density of neutrophils and stromal cells. Relative cross-sectional area of apoptotic, neutrophil-rich, neutrophil+stromal and stromal tissues in sections collected (A) at the edge and (B) through the middle of treated defects in collagen type I-stained cryosections (N=4). Apoptotic tissues cover a larger area in the middle of 150K-treated defects after 21 days than 40K and 10K-treated defects (p=0.0417, p=0.0515, respectively). (C) Volume density (Vv) of neutrophils and stromal cells in 40x magnification pictures of neutrophil-rich, neutrophil+stromal and stromal tissues in the middle of day 21 treated defects of collagen type I-stained cryosections (N=4).

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