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Table 9 Allele frequencies of four polymorphisms in ONFH patients in the relation to number of affected joints (total, unilateral and bilateral ONFH) and controls

From: Prevalence of genetic risk factors related with thrombophilia and hypofibrinolysis in patients with osteonecrosis of the femoral head in Poland

Allele

Controls N=200

Patients

Total N=136

Unilateral n=58

Bilateral n=78

Factor V Leiden

A

0,03

0,0225

0,0334

0,0128

G

0,97

0,9775

0,9656

0,9872

Prothrombin

A

0,01

0,0074

0,0175

0

G

0,99

0,9926

0,9825

1,0

MTHFR

T

0,28

0,3161

0,3103

0,3205

C

0,72

0,6839

0,6897

0,6795

TPA

D

0,365

0,4705a

0,3965

0,5256b

I

0,6350

0,5295

0,6035

0,4744

  1. ap =0,026; odds ratio (OR) 1,54; 95% confidence intervals (CIs) 0,99-2,4.
  2. bp= 0,01; OR= 1,92; 95% CIs 1,13-3,27.
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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