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Table 8 Genotype frequencies of four polymorphisms in ONFH patients in the relation to age (total, <50 and >50) and controls

From: Prevalence of genetic risk factors related with thrombophilia and hypofibrinolysis in patients with osteonecrosis of the femoral head in Poland

Genotype

Controls N=100

Patients

Total N=68

<50 n=43

>50 n=25

Factor V Leiden

GA

3(3%)

3(4,41%)

3(6,67%)

0

GG

97(97%)

65(95,59%)

40(93,33%)

25(100%)

Prothrombin

GA

2(2%)

1(1,47%)

1 (2,38%)

0

GG

98(98%)

67(98,53%)

42(97,62%)

25(100%)

MTHFR

TT

7(7%)

4(5,88%)

1(2,32%)

3(12%)

CT

42(42%)

35(51,47%)

22(51,16%)

13(52%)

CC

51(51%)

29(42,65%)

20(46.52%)

9(36%)

TPA

DD

18(18%)

13(19,12%)

8(18,6%)

5(20%)

ID

37(37%)

38(55,88%)a

21(48.83%)

17(68%)b

II

45(45%)

17(25%)

14(32,57%)

3(12%)

  1. ap=0,004; odds ratio(OR ) 2,71; 95% confidence intervals (CIs) 1,32-5,57.
  2. bp=0,001; OR 6,89; 95% CIs 1,87-25,84.