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Table 6 Genotype frequencies of four polymorphisms in ONFH patients in the relation to gender (total, female and male) and controls

From: Prevalence of genetic risk factors related with thrombophilia and hypofibrinolysis in patients with osteonecrosis of the femoral head in Poland

Genotype

Controls N=100

Patients

Total N=68

Female n=12

Male n=56

Factor V Leiden

GA

3(3%)

3(4,41%)

0

3(5,66%)

GG

97(97%)

65(95,59%)

12(100%)

53(94,34%)

Prothrombin

GA

2(2%)

1(1,47%)

0

1(1,78%)

GG

98(98%)

67(98,53%)

12(100%)

55(98,22%)

MTHFR

TT

7(7%)

4(5,88%)

2(18,66%)

2(3,57%)

CT

42(42%)

35(51,47%)

7(56,34%)

28(50,01%)

CC

51(51%)

29(42,65%)

3(25%)

26(46,42%)

TPA

DD

18(18%)

13(19,12%)

2(16,66%)

11(19,64%)

ID

37(37%)

38(55,88%)a

4(33,34%)

34(60,72%)b

II

45(45%)

17(25%)

6(50,0%)

11(19,64%)

  1. ap=0,004; odds ratio(OR ) 2,71; 95% confidence intervals (CIs) 1,32-5,57.
  2. bp=0,0007; OR 3,75; 95% CIs 1,67-8,42.