Skip to main content

Table 6 Observed and expected risk ratios of having a total joint replacement associated with smoking: one-way sensitivity analysis accounting for uncertainty in the classification of smoking exposure

From: Smoking and primary total hip or knee replacement due to osteoarthritis in 54,288 elderly men and women

 

Level of uncertainty!

Sensitivity!!

Risk ratio (95% CI)

P value

Observed risk ratio

-

-

0.62 (0.54 – 0.72)

<0.001

Expected risk ratios based on one-way sensitivity analyses!!!

1%

.99

0.66 (0.58 – 0.75)

<0.001

 

5%

.95

0.76 (0.68 – 0.84)

<0.001

 

10%

.90

0.82 (0.75 – 0.90)

<0.001

 

20%

.80

0.89 (0.82 – 0.95)

0.001

 

25%

.75

0.90 (0.84 – 0.97)

0.004

 

30%

.70

0.92 (0.86 – 0.98)

0.009

 

40%

.60

0.93 (0.88 – 0.99)

0.032

 

50%

.50

0.94 (0.89 – 1.01)

0.073

  1. !Uncertainty in the classification of smoking. The values represent hypothetical percentages of study participants potentially declining to reveal that they indeed did smoke.
  2. !!Sensitivity is defined as the probability of a true smoker being classified as a smoker.
  3. !!!The one way sensitivity analysis evaluated the risk ratio under various sensitivity measures while holding the specificity fixed.
Back to article page