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Table 5 Subdistribution hazard ratios of undergoing total hip or knee replacement: multivariable competing risk regressions ! - accounting for the competing risk of death (N = 44,614)

From: Smoking and primary total hip or knee replacement due to osteoarthritis in 54,288 elderly men and women

  Total hip replacement Total knee replacement
Covariates sHR (95% CI), P value sHR (95% CI), P value
Age, continuous 0.97 (0.96–0.98), <0.001 0.95 (0.94–0.96), <0.001
Female gender, yes 1.34 (1.21–1.49), <0.001 1.27 (1.16–1.39), <0.001
Charlson Index, continuous 0.79 (0.71–0.88), <0.001 0.70 (0.63–0.77), 0.001
BMI categories Kg/m2   
Normal weight 18.5-24.9 (ref) 1.00 1.00
Underweight <18.5 0.46 (0.22–0.97), 0.042 0.19 (0.06–0.58), 0.004
Overweight 25–29.9 1.46 (1.25–1.71), <0.001 1.68 (1.44–1.95), <0.001
Obese 30–34.9 1.66 (1.38–1.99), <0.001 2.81 (2.39–3.30), <0.001
Morbidly obese ≥ 35 1.57 (1.17–2.09), 0.002 3.72 (3.03–4.57), <0.001
Current smoker, yes 0.72 (0.58–0.90), 0.004 0.59 (0.48–0.73), 0.001
SEIFA score, continuous 1.00 (0.99–1.00), 0.115 1.00 (0.99–1.00), 0.083
Screening SBP, continuous 0.99 (0.99–0.99), 0.011 0.99 (0.99–0.99), <0.001
  1. !Also controlled for alcohol intake, physical exercise activity and screening diastolic blood pressure.
  2. Abbreviations: BMI (body mass index), SEIFA (Socio-Economic Indexes for Areas), SBP (systolic blood pressure), TJR (total joint replacement), sHR (subdistribution hazard ratio).