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Table 5 Subdistribution hazard ratios of undergoing total hip or knee replacement: multivariable competing risk regressions ! - accounting for the competing risk of death (N = 44,614)

From: Smoking and primary total hip or knee replacement due to osteoarthritis in 54,288 elderly men and women

 

Total hip replacement

Total knee replacement

Covariates

sHR (95% CI), P value

sHR (95% CI), P value

Age, continuous

0.97 (0.96–0.98), <0.001

0.95 (0.94–0.96), <0.001

Female gender, yes

1.34 (1.21–1.49), <0.001

1.27 (1.16–1.39), <0.001

Charlson Index, continuous

0.79 (0.71–0.88), <0.001

0.70 (0.63–0.77), 0.001

BMI categories

Kg/m2

  

Normal weight

18.5-24.9 (ref)

1.00

1.00

Underweight

<18.5

0.46 (0.22–0.97), 0.042

0.19 (0.06–0.58), 0.004

Overweight

25–29.9

1.46 (1.25–1.71), <0.001

1.68 (1.44–1.95), <0.001

Obese

30–34.9

1.66 (1.38–1.99), <0.001

2.81 (2.39–3.30), <0.001

Morbidly obese

≥ 35

1.57 (1.17–2.09), 0.002

3.72 (3.03–4.57), <0.001

Current smoker, yes

0.72 (0.58–0.90), 0.004

0.59 (0.48–0.73), 0.001

SEIFA score, continuous

1.00 (0.99–1.00), 0.115

1.00 (0.99–1.00), 0.083

Screening SBP, continuous

0.99 (0.99–0.99), 0.011

0.99 (0.99–0.99), <0.001

  1. !Also controlled for alcohol intake, physical exercise activity and screening diastolic blood pressure.
  2. Abbreviations: BMI (body mass index), SEIFA (Socio-Economic Indexes for Areas), SBP (systolic blood pressure), TJR (total joint replacement), sHR (subdistribution hazard ratio).
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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