Table 4 Changes in secondary efficacy variables
Time after first application of study drug | ||||||
|---|---|---|---|---|---|---|
24 hours | 48 hours | 96 hours | ||||
Efficacy variable | DDEA 1.16% gel | Placebo | DDEA 1.16% gel | Placebo | DDEA 1.16% gel | Placebo |
Pain-at-rest – mean ± SD, mm (% difference from baseline) | 18.5 ± 11.3* (55.0) | 36.3 ± 16.0 (9.5) | 6.5 ± 7.6* (84.2) | 29.2 ± 15.7 (27.2) | 1.2 ± 2.9* (97.1) | 19.2 ± 11.9 (52.1) |
Neck disability index score – mean ± SD (% difference from baseline) | 16.0 ± 7.1* (36.8) | 21.9 ± 7.9 (7.2) | 7.8 ± 2.9* (69.2) | 19.9 ± 8.4 (15.7) | 2.8 ± 3.0* (88.9) | 14.6 ± 6.8 (38.1) |