Efficacy and safety of diclofenac diethylamine 1.16% gel in acute neck pain: a randomized, double-blind, placebo-controlled study

Table 3 Pain-on-movement at 48 h (primary efficacy variable)

Mean (SD) [mm]		LS * mean (SE) [mm]		LS mean difference (SE) 95% CI	p-value^†
DDEA 1.16% gel (N = 36)	Placebo	DDEA 1.16% gel (N = 36)	Placebo	Placebo – DDEA 1.16% gel
DDEA 1.16% gel (N = 36)	(N = 36)	DDEA 1.16% gel (N = 36)	(N = 36)	Placebo – DDEA 1.16% gel
19.5 (12.9)	56.9 (16.1)	17.8 (2.1)	56.3 (2.4)	38.4 (3.0)	p < 0.0001
				32.4–44.5

* LS-mean – Least squares mean difference adjusted for effects of site and baseline POM; ^† ANCOVA – Analysis-of-covariance test with treatment and site as main effects and the baseline POM as a covariate.
DDEA = diclofenac diethylamine; SD = standard deviation; SE = standard error; CI = confidence interval.

ISSN: 1471-2474