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Table 4 Univariate associations between cardiac involvement and clinical data in 210 patients with ankylosing spondylitis

From: Cardiac conduction system abnormalities in ankylosing spondylitis: a cross-sectional study

 

PQ interval

 

QRS interval

 

AVB IVCD

 

AVB IVCDx

 
 

Beta (95% CI)

p

Beta (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

Age

0.47 ( 0.19,0.74)

.001

0.10 (−0.04,0.25)

.17

1.088 (1.040,1.138)

.0003

1.070 (1.033,1.109)

.0002

Male gender

15.3 (8.2,22.4)

<.0001

10.8 (7.3,14.3)

<.0001

8.28 (1.88,36.53)

.005

4.70 (1.73,12.80)

.002

Age spt onset

0.27 (−0.12,0.66)

.17

0.12 (−0.08,0.32)

.24

1.002 (0.956,1.051)

.92

1.015 (0.976,1.055)

.46

Symptom dur.

0.38 ( 0.09,0.67)

.01

0.02 (−0.13,0.17)

.79

1.069 (1.030,1.111)

.0005

1.055 (1.023,1.088)

.0007

BASDAI

−0.16 (−0.88,1.56)

.86

−0.93 (−1.78,-0.09)

.03

0.993 (0.801,1.232)

.95

0.997 (0.832,1.194)

.97

BASFI

1.68 (−0.09,3.46)

.06

−0.44 (−1.33,0.45)

.33

1.207 (0.984,1.479)

.07

1.239 (1.041,1.474)

.02

BASMI

3.42 ( 1.12,5.72)

.004

0.24 (−0.95,1.44)

.69

1.593 (1.224,2.074)

.0005

1.566 (1.241,1.975)

.0002

Length

−0.61 ( 0.24,0.97)

.001

0.52 ( 0.35,0.70)

<.0001

1.060 (1.009,1.114)

.02

1.048 (1.006,1.092)

.02

Weight

0.52 ( 0.31,0.74)

<.0001

0.29 ( 0.18,0.40)

<.0001

1.039 (1.012,1.067)

.005

1.051 (1.025,1.077)

<.0001

BMI

0.66 (−0.14,1.46)

.11

0.40 (−0.01,0.81)

.05

0.956 (0.857,1.068)

.43

1.011 (0.931,1.097)

.80

Hb

0.57 ( 0.29,0.85)

<.0001

0.27 ( 0.13,0.42)

.0002

1.027 (0.989,1.066)

.17

1.038 (1.005,1.073)

.02

ESR

−0.09 (−0.36,0.18)

.49

−0.10 (−0.24,0.03)

.14

1.007 (0.977,1.038)

.65

0.991 (0.959,1.023)

.56

CRP

−0.04 (−0.41,0.33)

.82

−0.04 (−0.22,0.15)

.69

1.025 (0.994,1.058)

.12

1.021 (0.992,1.052)

.16

WBC

−1.79 (−3.51,-0.07)

.04

−0.56 (−1.43,0.32)

.21

0.977 (0.787,1.213)

.83

0.863 (0.700,1.063)

.17

PLT

−0.05 (−0.10,-0.00)

.05

−0.01 (−0.04,0.01)

.37

0.998 (0.992,1.004)

.58

0.995 (0.990,1.001)

.10

B27 alleles

6.2 (−4.8,17.2)

.27

−0.2 (−5.9,5.4)

.93

3.21 (0.41,24.95)

.26

2.37 (0.53,10.55)

.26

  1. AVB IVCD denotes atrio-ventricular and intra-ventricular conduction disturbances according to standard (conservative) criteria (n = 21).
  2. AVB IVCDx denotes such disturbances according to less conservative criteria (n==31) for comparison with ref.[13].
  3. Abbreviations: PQ interval = duration from P-wave to QRS complex; QRS interval = duration of QRS complex; AVB atrio-ventricular Block; IVCD intra-ventricular conduction disturbances: BASDAI Bath Ankylosing Spondylitis Disease Activity Index; BASFI Bath Ankylosing Spondylitis Functional Index; BASMI Bath Ankylosing Spondylitis Metrology Index; BMI Body Mass Index; Hb Hemoglobin (g/L); ESR Erythrocyte Sedimentation Rate (mm/h); CRP C-reactive protein (mg/L); WBC White Blood Cells (×109/L); PLT Platelet Count (×109/L).
  4. Beta regression coefficient; CI confidence interval; OR = odds ratio.
  5. Univariate associations (univariate linear regression and logistic regression).