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Figure 1 | BMC Musculoskeletal Disorders

Figure 1

From: Mitochondrial respiratory chain dysfunction modulates metalloproteases -1, -3 and -13 in human normal chondrocytes in culture

Figure 1

mRNA expression of MMPs-1, -3 and -13 in chondrocytes after MRC dysfunction. Chondrocytes were cultured in 6 well plates in basal conditions or with Rotenone (10 and 50 μg/mL), NPA (0.5 and 10 mM), AA (20 and 60 μg/mL), Sodium azide (2 and 25 mM) or Oligomycin (5 and 100 μg/mL) for 24 h. The mRNA was purified and PCR was conducted in order to analyze MMP-1 (A), MMP-3 (B) and MMP-13 expression (C). Data are represented as mean ± SE of 9 independent experiments in duplo.

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