Effects of neuromuscular training (NEMEX-TJR) on patient-reported outcomes and physical function in severe primary hip or knee osteoarthritis: a controlled before-and-after study

Table 3 Change in outcome measures baseline vs. follow-up in patients and references

		Change baseline vs follow-up
		Total OA group	Hip OA	Knee OA	References
		(n = 83 to 87)	(n = 31 to 38)	(n = 45 to 49)	(n = 41 to 43)
		Mean diff (95% CI)	Mean diff (95% CI)	Mean diff (95% CI)	Mean diff (95% CI)
Patient-reported outcomes
HOOS/KOOS subscales
	Pain	5.7(3.3;8.0)	6.1(2.9;9.3)	5.3(1.9;8.7)	0.5(−3.1;4.1)
	Symptoms	4.2(1.3;7.2)	4.7(0.1;9.4)	3.8(0.1;7.7)	2.1(−2.4;6.7)
	ADL	7.1(4.8;9.3)	5.0(1.7;8.3)	8.5(5.4;11.7)	−1.0(−4.5;2.5)
	Sport/Rec	4.5(1.3;7.6)	6.9(1.1;12.8)	2.4(0.8;5.6)	0.5(−4.4;5.4)
	QOL	5.8(3.1;8.6)	7.1(3.7;10.6)	4.8(0.7;9.0)	2.1 (−2.8;6.9)
Physical function
Chair stands (sec)		−3.24(−4.29;-2.20)	−3.23(−4.33;-2.13)	−3.26(−4.96;-1.57)	−0.88(−1.33;-0.43)
Knee bendings/30 sec affected leg (n)^‡		2.3(0.3;4.4)	4.0(1.4;6.7)	0.1(−3.1;3.2)	1.8(0.5;3.2)^†
Knee bendings/30 sec non-affected leg (n)^‡		1.4(−0.0;2.8)	2.3(−0.1;4.7)	0.6(−1.0;2.1)	1.8(0.5;3.2)^†
Knee ext affected leg (kg)		1.7(1.1;2.4)	1.9(0.9;2.7)	1.5(0.6;2.4)	0.2(−0.7;1.1)^†
Knee ext non-affected leg (kg)		1.0(0.3;1.6)	1.2(0.1;2.3)	0.8(0.1;1.7)	0.2(−0.7;1.1)^†
20-m walk test, time (sec)		−1.34(−1.97;-0.72)	−1.09(−1.85;-0.32)	−1.55(−2.51;-0.59)	−0.03(−0.32;0.26)
20-m walk test, steps (n)		−1.5(−2.3;-0.6)	−1.0(−1.9;-0.1)	−1.8(−3.1;-0.5)	−0.1(−0.5;0.3)

^†Right leg in references used for comparison with patients’ affected and non-affected legs.
A negative value for chair stands and 20-m walk test (sec and steps) indicates improvement. For all other variables, a positive value indicates improvement.
^‡Could not perform the test: Total OA group: affected leg n = 33, non-affected leg n = 15; Hip OA: affected leg n = 9, non-affected leg n = 4; Knee OA: affected leg n = 24, non-affected leg n = 11.
Ext = extension strength.
CI = confidence interval. Confidence intervals not containing zero indicate statistical significance.

ISSN: 1471-2474