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Table 3 Change in outcome measures baseline vs. follow-up in patients and references

From: Effects of neuromuscular training (NEMEX-TJR) on patient-reported outcomes and physical function in severe primary hip or knee osteoarthritis: a controlled before-and-after study

  Change baseline vs follow-up
  Total OA group Hip OA Knee OA References
  (n = 83 to 87) (n = 31 to 38) (n = 45 to 49) (n = 41 to 43)
  Mean diff (95% CI) Mean diff (95% CI) Mean diff (95% CI) Mean diff (95% CI)
Patient-reported outcomes     
HOOS/KOOS subscales     
  Pain 5.7(3.3;8.0) 6.1(2.9;9.3) 5.3(1.9;8.7) 0.5(−3.1;4.1)
  Symptoms 4.2(1.3;7.2) 4.7(0.1;9.4) 3.8(0.1;7.7) 2.1(−2.4;6.7)
  ADL 7.1(4.8;9.3) 5.0(1.7;8.3) 8.5(5.4;11.7) −1.0(−4.5;2.5)
  Sport/Rec 4.5(1.3;7.6) 6.9(1.1;12.8) 2.4(0.8;5.6) 0.5(−4.4;5.4)
  QOL 5.8(3.1;8.6) 7.1(3.7;10.6) 4.8(0.7;9.0) 2.1 (−2.8;6.9)
Physical function     
Chair stands (sec) −3.24(−4.29;-2.20) −3.23(−4.33;-2.13) −3.26(−4.96;-1.57) −0.88(−1.33;-0.43)
Knee bendings/30 sec affected leg (n) 2.3(0.3;4.4) 4.0(1.4;6.7) 0.1(−3.1;3.2) 1.8(0.5;3.2)
Knee bendings/30 sec non-affected leg (n) 1.4(−0.0;2.8) 2.3(−0.1;4.7) 0.6(−1.0;2.1)
Knee ext affected leg (kg) 1.7(1.1;2.4) 1.9(0.9;2.7) 1.5(0.6;2.4) 0.2(−0.7;1.1)
Knee ext non-affected leg (kg) 1.0(0.3;1.6) 1.2(0.1;2.3) 0.8(0.1;1.7)
20-m walk test, time (sec) −1.34(−1.97;-0.72) −1.09(−1.85;-0.32) −1.55(−2.51;-0.59) −0.03(−0.32;0.26)
20-m walk test, steps (n) −1.5(−2.3;-0.6) −1.0(−1.9;-0.1) −1.8(−3.1;-0.5) −0.1(−0.5;0.3)
  1. Right leg in references used for comparison with patients’ affected and non-affected legs.
  2. A negative value for chair stands and 20-m walk test (sec and steps) indicates improvement. For all other variables, a positive value indicates improvement.
  3. Could not perform the test: Total OA group: affected leg n = 33, non-affected leg n = 15; Hip OA: affected leg n = 9, non-affected leg n = 4; Knee OA: affected leg n = 24, non-affected leg n = 11.
  4. Ext = extension strength.
  5. CI = confidence interval. Confidence intervals not containing zero indicate statistical significance.