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Table 2 Bone mineral density and laboratory results at baseline, 48 and 96 weeks

From: Bone turnover and bone mineral density in HIV-1 infected Chinese taking highly active antiretroviral therapy –a prospective observational study

 

HIV-infected patients

p- value #

Variables

Baseline

Week 48

Week 96

 

BMD (mean g/ cm 2 )

    

  Lumbar spine

1.138 ± 0.112

1.112 ± 0.113

1.120 ± 0.111

0.022

  Femoral neck

0.972 ± 0.136

0.940 ± 0.135

0.942 ± 0.133

0.000

  Total hip

1.015 ± 0.147

0.996 ± 0.142

0.996 ± 0.140

0.002

BMD (mean Z score)

    

  Lumbar spine

0.511 ± 0.838

0.288 ± 0.902

0.550 ± 0.691

0.053

  Femoral neck

0.255 ± 1.018

-0.0125 ± 0.942

0.177 ± 0.831

0.014

  Total hip

0.244 ± 1.102

0.105 ± 1.033

0.412 ± 1.004

0.164

β-CTX (mean ng/ mL)

0.31 ± 0.16

0.41 ± 0.13

0.36 ± 0.12

0.000

P1NP (mean ng/ mL)

32.96 ± 14.00

50.91 ± 21.97

49.53 ± 17.32

0.000

PTH (mean pg/ mL)

41.78 ± 16.11

51.81 ± 15.96

65.06 ±20.59

0.000

25- OH vitamin D (mean ng/ mL)

15.93 ± 6.49

15.04 ± 7.14

13.77 ± 7.16

0.343

  1. Illustrations for Table 2. BMD: bone mineral density; lumbar spine: the first to fourth lumbar vertebrae; P1NP: procollagen type 1 N-terminal propeptide; β-CTX: Type I collagen cross-linked C-telopeptide; PTH: parathyroid hormone. # P-value indicates comparison between baseline and week48.