Table 2 Genotypic frequencies in the present study and for WHITE (HapMap CEU), Black African (HapMap YRI) and Hispanic (HISP1) populations in NCBI dbSNP
Gene | Genotype | Population | p-value | ||||||
|---|---|---|---|---|---|---|---|---|---|
Total | White | Black African | Hispanic | ||||||
Present study | Present study | HapMap | Present study | HapMap | Present study | HapMap | |||
N = 73 | N = 43 | CEU | N = 11 | YRI | N = 19 | HISP1 | |||
ELN | AA | 27.40% | 14% | 15.50% | 45.45% | 40.20% | 47.40% | n/a | < 0.0001 |
AG | 56.20% | 65.10% | 65.11% | 36.40% | 44.20% | 47.40% | n/a | ||
GG | 16.40% | 20.90% | 36.40% | 18.20% | 15.20% | 5.20% | n/a | ||
TTN | AA | 50.70% | 58.10% | 68.10% | 27.30% | 14.20% | 47.40% | n/a | < 0.0001 |
AG | 39.70% | 37.20% | 26.50% | 45.50% | 46.90% | 42.10% | n/a | ||
GG | 9.60% | 4.70% | 5.30% | 27.30% | 38.90% | 10.50% | n/a | ||
SOX15 | TT | 58.90% | 62.80% | 58.40% | 36.40% | 20.40% | 63.20% | 52.20% | < 0.0001 |
TG | 31.50% | 32.60% | 33.60% | 36.40% | 49.60% | 26.30% | 34.80% | ||
GG | 9.60% | 4.70% | 8.00% | 27.30% | 30.10% | 10.50% | 13.00% | ||
IGF2 | GG | 38.40% | 30.20% | 30.10% | 45.45% | 38.10% | 52.60% | 43.50% | < 0.0001 |
GC | 43.80% | 53.50% | 53.10% | 27.30% | 42.30% | 31.60% | 21.70% | ||
CC | 17.80% | 16.30% | 16.80% | 27.30% | 9.20% | 15.80% | 34.80% | ||
CCL2 | GG | 43.80% | 39.50% | 65.20% | 54.50% | 52.20% | 47.40% | n/a | < 0.0001 |
GC | 46.60% | 48.80% | 30.40% | 45.50% | 34.80% | 42.10% | n/a | ||
CC | 9.60% | 11.60% | 4.03% | - | 13% | 10.50% | n/a | ||
TNC | AA | 35.60% | 30.20% | 31.70% | 45.45% | 46.70% | 42.10% | n/a | < 0.0001 |
AT | 43.80% | 51.20% | 53.30% | 36.40% | 41.70% | 31.60% | n/a | ||
TT | 20.50% | 18.60% | 15.00% | 18.20% | 11.70% | 26.30% | n/a | ||
COL1A1 | GG | 71.20% | 72.10% | - | 81.80% | 100% | 63.20% | n/a | < 0.0001 |
GA | 26% | 23.30% | 100% | 18.20% | - | 36.80% | n/a | ||
AA | 2.70% | 4.65% | - | - | - | - | n/a | ||
COL5A1 | TT | - | - | 24.50% | - | - | - | n/a | < 0.0001 |
TC | 65.30% | 76.20% | 64.20% | 18.20% | 27.10% | 68.40% | n/a | ||
CC | 34.70% | 23.80% | 11.30% | 81.80% | 72.90% | 31.60% | n/a | ||