Table 4 Adjusted associations of BMI and activity (occupational/ leisure) at 36, 43, and 53 years with kOA in women

Manual occupation

1.85 (1.06, 3.24)

0.031

1.09 (0.66, 1.82)

0.734

1.87 (1.22, 2.86)

0.004

Non-manual occupation

Referent

Referent

Referent

BMI (per z-score)

1.49 (1.16, 1.91)

0.002

1.73 (1.39, 2.15)

<0.001

1.92 (1.59, 2.33)

<0.001

 p-value for test of interaction

0.691

0.570

0.203

Lifting unlikely

0.89 (0.51, 1.55)

0.681

1.10 (0.67, 1.81)

0.710

0.71 (0.42, 1.19)

0.317

Lifting somewhat likely

Referent

Referent

Referent

Lifting highly likely

0.73 (0.32, 1.66)

0.449

1.09 (0.55, 2.18)

0.070

1.02 (0.51, 2.07)

0.590

BMI (per z-score)

1.80 (1.47, 2.21)

<0.001

1.85 (1.52, 2.25)

<0.001

1.73 (1.49, 2.24)

<0.001

 p-value for test of interaction

0.344

0.580

0.808

Kneeling unlikely

0.74 (0.49, 1.11)

0.143

0.79 (0.52, 1.18)

0.248

0.93 (0.58, 1.51)

0.776

Kneeling somewhat likely

Referent

Referent

Referent

Kneeling highly likely

0.91 (0.45, 1.85)

0.793

0.80 (0.41, 1.59)

0.530

1.23 (0.58, 2.61)

0.582

BMI (per z-score)

1.78 (1.45, 2.18)

<0.001

1.83 (1.50, 2.22)

<0.001

1.91 (1.29, 2.83)

<0.001

 p-value for test of interaction

0.295

0.780

0.405

Sitting unlikely

1.15 (0.72, 1.84)

0.549

0.76 (0.47, 1.24)

0.276

1.29 (0.77, 2.16)

0.343

Sitting somewhat likely

Referent

Referent

Referent

Sitting highly likely

0.56 (0.33, 0.94)

0.029

0.57 (0.36, 0.89)

0.013

0.89 (0.56, 1.43)

0.653

BMI (per z-score)

1.77 (1.45, 2.18)

<0.001

1.80 (1.48, 2.19)

<0.001

1.48 (1.41, 2.22)

<0.001

 p-value for test of interaction

0.292

0.846

0.234

Inactive

1.00 (0.63, 1.60)

0.985

0.73 (0.47, 1.13)

0.153

1.46 (0.87, 2.47)

0.154

Less active

Referent

Referent

Referent

Most active

0.99 (0.61, 1.63)

0.978

0.50 (0.28, 0.91)

0.022

0.67 (0.37, 1.21)

0.184

BMI (per z-score)

1.85 (1.51, 2.25)

<0.001

1.82 (1.50, 2.20)

<0.001

1.84 (1.52, 2.23)

<0.001

 p-value for test of interaction

0.118

0.005

0.414