Figure 3

Results of Western blotting analysis. A. Western blotting of p38, p-p38, JNK, p-JNK, ATF2 and p-ATF2 in cartilage and chondrocytes both from KBD patient samples. p-JNK, ATF2 and p-ATF2 could not be detected in chondrocytes from KBD patients. B. Western blotting of p-p38, p-JNK, ATF2 and p-ATF2 in normal and KBD cartilage samples. p-ATF2 could not be detected in normal cartilage. C. Western blotting of p-p38, p-JNK, ATF2 and p-ATF2 in cartilage and chondrocytes both from normal samples. The levels of p-p38, p-JNK, ATF2 were higher in cartilage than cultured chondrocytes and p-ATF2 was absent in cartilage and chondrocytes. * p < 0.05, * * p < 0.01.