#: Number of the animals with the histopathological finding.
%: Percentage of the animals with the histopathological finding
As for degeneration, necrosis, or regeneration of muscle fiber, when a few mass or affected muscle bundles were observed in several scattered areas, the finding was judged positive. Atrophy was diagnosed when width of the muscle bundle was smaller than half width of normal bundle. The number of animals with the above lesions was summarized in Table 1.