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Table 4 Measures included in the comprehensive clinical examination (CE)

From: Hand, hip and knee osteoarthritis in a Norwegian population-based study - The MUST protocol

Measure Measurement scale
Medical examination
Lenght of time with OA disease Year of OA diagnosis
Lenght of time with OA symptoms Year when first experienced OA symptoms
Dominant hand Right/left
Dominant leg Right/left
Father with OA Yes/No
Mother with OA Yes/No
Siblings with OA Yes/No
Tegner activity scale[81] 0-5
Stroke test[80] 0-3
Soft tissue swelling joint count (SJC) Shoulder, acromioclavicular (AC), elbow, wrist, CMC, MCP, PIP, DIP, hip, knee, ankle, metatarsophalangeal (MTP); Yes/No
Bony enlargement joint count (BEJC) Shoulder, AC, elbow, wrist, CMC, MCP, PIP, DIP, hip, knee, ankle, MTP; Yes/No
Tender joint count (TJC) Shoulder, AC, elbow, wrist, CMC, MCP, PIP, DIP, hip, knee, ankle, MTP+ cervical columna, thoracal columna, lumbal colulma; Yes/No
Limited motion joint count (LMJC) Shoulder, AC, elbow, wrist, CMC, MCP, PIP, DIP, hip, knee, ankle, MTP+ cervical columna, thoracal columna, lumbal colulma; Yes/No
ACR classification criteria for hip OA[17] Hip pain AND at least 2 of the following 3 features: erythrocyte sedimentation rate (ESR) <20mm/hour, radiographic femoral or acetabular osteophytes, radiographic joint space narrowing
ACR clinical classification criteria for knee OA[16] Knee pain AND at least 3 of 6 of the following features: age > 50, stiffness < 30 min, crepitus, bony tenderness, bony enlargement, no palpable warmth
ACR classification criteria for hand OA[18] Hand pain, aching or stiffness AND 3 or 5 of the following features: hard tissue enlargement of ≥2 of 10 selected joints, hard tissue enlargement of ≥2 DIP joints, fewer than 3 swollen MCP joints, deformity of ≥1 of 10 selected joints (bilateral 2nd-3rd DIP, 2nd-3rd PIP, and 1st CMC)
Doctor global assessment of OA disease NRS: 0-10
Physical function examination
Range of movement Hip: flexion, extension, abduction, internal rotation, external rotation
Knee: flexion, extension
Beighton scale[88] 0-9
Maximum grip strenght (JAMAR dynamometer) Kilograms (mean of 3 repetitions)
Moberg Pick Up Test[85] Seconds (Left/Right hand)
30 sec Timed Stand Stands[87] Number of stands
6 Minutes Walk Test[86] Meters
Leg pain during 6 Minutes Walk Test Yes/No + NRS: 0-10
Imaging
Magnetic resonance imaging Synovitis grade 0-3, flexor tenosynovitis grade 0-3, erosion grade 0-3, cyst absent/present, osteophyte grade 0-3, joint space narrowing grade 0-3, malalignment absent/present, bone marrow lesion grade 0-3, collateral ligament pathology absent/present (the Oslo hand OA MRI score)
Dominant hand (only when self-reported hand OA)
Conventional radiographs  
Hip joints, bilateral Millimetre joint space width
Knee joints, bilateral Kellgren and Lawrence scale: grade 0-4
OARSI: medial and lateral femoral condyle/medial and lateral tibial plateau osteophyte grade 0-3+, medial and lateral compartment joint space narrowing grade 0-3+, medial tibial attrition absent/present, medial tibial sclerosis absent/present, lateral femoral sclerosis absent/present
Hand joints, bilateral Kellgren and Lawrence scale: grade 0-4
OARSI: osteophyte grade 0-3, joint space narrowing grade 0-3, malalignment absent/present, erosion absent/present sclerosis absent/present, cyst absent/present
Ultrasound  
HIP joint osteophytes 0, none; 1, minor; 2, moderate; 3, major size of osteophytes
Capsule diameter caput Millimetre
Capsule diameter collum Millimetre
Capsule shape 0, concave; 1, flat; 2, convex
Caput femoris shape 0, normal; 1, minor flattening; 2, considerably changed shape
Groin pain last week 0, no pain; 1, some pain; 2, moderate pain; 3, severe pain
KNEE joint osteophytes, femur medial and lateral 0, none; 1, minor; 2, moderate; 3, major size of osteophytes
Knee joint osteophytes, tibia medial and lateral 0, none; 1, minor; 2, moderate; 3, major size of osteophytes
Lateral and medial menisci protrusion 0, none; 1, minor; 2, major
Synovitis in the suprapatellar recess (combined synovitis and effusion) 0, none; 1, minor; 2, moderate; 3, major
Femur cartilage height at sulcus, lateral, and medial condyle Milimeter
Femur cartilage quality, Degree of hyperechogenisity 0, normal; 1 minor; 2 major
Femur hyaline cartilage, Calcium crystal pyrophosphate deposition (CPPD) 0, none; 1, presence of CPPD changes
Kne pain last week 0, no pain; 1, some pain; 2, moderate pain; 3, severe pain
HAND joint osteophytes 30 joints: 0, none; 1, minor; 2, moderate; 3, major size of osteophytes
Hand joint synovitis (combined synovitis and effusion) 30 joints: 0, none; 1, minor; 2, moderate; 3, major
Hand joint vascularity 30 joints: 0, none; 1, minor (1-2 small vessels); 2, moderate; 3, major
Cardiovascular examination
Heart rate Beats per minute
Systolic blood pressure (monitor) mmHg
Diastolic blood pressure (monitor) mmHg
Ankle brachial index (ABI) Systolic blood pressure leg (mmHg)/ Systolic blood pressure arm (mmHg)
Arterial stiffness Pulse wave velocity, augmentation index
ECG Electrocardiogram
Surgery/injuries
Hip prosthesis Yes/No; Right/Left; Year of surgery
Hip surgery/injury Yes/No; Right/Left; Type surgery/injury; Type treatment; MD/Hospital
Knee prosthesis Yes/No; Right/Left; Year of surgery
Knee surgery/injury Yes/No; Right/Left; Type surgery/injury; Type treatment; MD/Hospital
Hand surgery/injury Yes/No; Right/Left; Type surgery/injury; Type treatment; MD/Hospital
Hand synovectomy Yes/No; Number of operations
Hand joint prosthesis Yes/No; Number of operations
Hand joint fusion Yes/No; Number of operations
Other operations on hand joints or tendons Yes/No; Number of operations
Anthropometric data
Body weight Centimeters
Body height Kilograms
Hip circumference Centimeters
Waist circumference Centimeters
Digital photo of hands Standardised photo from above, both hands on top of a black fabric on a small tray
Biological samples
Blood haemoglobin g/dL
Blood erythrocyte sedimentation rate (ESR) mm/h, whole blood and blood serum are stored in a biobank
Urine Are stored in a biobank