From: Hand, hip and knee osteoarthritis in a Norwegian population-based study - The MUST protocol
Measure | Measurement scale |
---|---|
Medical examination | |
Lenght of time with OA disease | Year of OA diagnosis |
Lenght of time with OA symptoms | Year when first experienced OA symptoms |
Dominant hand | Right/left |
Dominant leg | Right/left |
Father with OA | Yes/No |
Mother with OA | Yes/No |
Siblings with OA | Yes/No |
Tegner activity scale[81] | 0-5 |
Stroke test[80] | 0-3 |
Soft tissue swelling joint count (SJC) | Shoulder, acromioclavicular (AC), elbow, wrist, CMC, MCP, PIP, DIP, hip, knee, ankle, metatarsophalangeal (MTP); Yes/No |
Bony enlargement joint count (BEJC) | Shoulder, AC, elbow, wrist, CMC, MCP, PIP, DIP, hip, knee, ankle, MTP; Yes/No |
Tender joint count (TJC) | Shoulder, AC, elbow, wrist, CMC, MCP, PIP, DIP, hip, knee, ankle, MTP+ cervical columna, thoracal columna, lumbal colulma; Yes/No |
Limited motion joint count (LMJC) | Shoulder, AC, elbow, wrist, CMC, MCP, PIP, DIP, hip, knee, ankle, MTP+ cervical columna, thoracal columna, lumbal colulma; Yes/No |
ACR classification criteria for hip OA[17] | Hip pain AND at least 2 of the following 3 features: erythrocyte sedimentation rate (ESR) <20mm/hour, radiographic femoral or acetabular osteophytes, radiographic joint space narrowing |
ACR clinical classification criteria for knee OA[16] | Knee pain AND at least 3 of 6 of the following features: age > 50, stiffness < 30 min, crepitus, bony tenderness, bony enlargement, no palpable warmth |
ACR classification criteria for hand OA[18] | Hand pain, aching or stiffness AND 3 or 5 of the following features: hard tissue enlargement of ≥2 of 10 selected joints, hard tissue enlargement of ≥2 DIP joints, fewer than 3 swollen MCP joints, deformity of ≥1 of 10 selected joints (bilateral 2nd-3rd DIP, 2nd-3rd PIP, and 1st CMC) |
Doctor global assessment of OA disease | NRS: 0-10 |
Physical function examination | |
Range of movement | Hip: flexion, extension, abduction, internal rotation, external rotation |
Knee: flexion, extension | |
Beighton scale[88] | 0-9 |
Maximum grip strenght (JAMAR dynamometer) | Kilograms (mean of 3 repetitions) |
Moberg Pick Up Test[85] | Seconds (Left/Right hand) |
30 sec Timed Stand Stands[87] | Number of stands |
6 Minutes Walk Test[86] | Meters |
Leg pain during 6 Minutes Walk Test | Yes/No + NRS: 0-10 |
Imaging | |
Magnetic resonance imaging | Synovitis grade 0-3, flexor tenosynovitis grade 0-3, erosion grade 0-3, cyst absent/present, osteophyte grade 0-3, joint space narrowing grade 0-3, malalignment absent/present, bone marrow lesion grade 0-3, collateral ligament pathology absent/present (the Oslo hand OA MRI score) |
Dominant hand (only when self-reported hand OA) | |
Conventional radiographs | Â |
Hip joints, bilateral | Millimetre joint space width |
Knee joints, bilateral | Kellgren and Lawrence scale: grade 0-4 |
OARSI: medial and lateral femoral condyle/medial and lateral tibial plateau osteophyte grade 0-3+, medial and lateral compartment joint space narrowing grade 0-3+, medial tibial attrition absent/present, medial tibial sclerosis absent/present, lateral femoral sclerosis absent/present | |
Hand joints, bilateral | Kellgren and Lawrence scale: grade 0-4 |
OARSI: osteophyte grade 0-3, joint space narrowing grade 0-3, malalignment absent/present, erosion absent/present sclerosis absent/present, cyst absent/present | |
Ultrasound | Â |
HIP joint osteophytes | 0, none; 1, minor; 2, moderate; 3, major size of osteophytes |
Capsule diameter caput | Millimetre |
Capsule diameter collum | Millimetre |
Capsule shape | 0, concave; 1, flat; 2, convex |
Caput femoris shape | 0, normal; 1, minor flattening; 2, considerably changed shape |
Groin pain last week | 0, no pain; 1, some pain; 2, moderate pain; 3, severe pain |
KNEE joint osteophytes, femur medial and lateral | 0, none; 1, minor; 2, moderate; 3, major size of osteophytes |
Knee joint osteophytes, tibia medial and lateral | 0, none; 1, minor; 2, moderate; 3, major size of osteophytes |
Lateral and medial menisci protrusion | 0, none; 1, minor; 2, major |
Synovitis in the suprapatellar recess (combined synovitis and effusion) | 0, none; 1, minor; 2, moderate; 3, major |
Femur cartilage height at sulcus, lateral, and medial condyle | Milimeter |
Femur cartilage quality, Degree of hyperechogenisity | 0, normal; 1 minor; 2 major |
Femur hyaline cartilage, Calcium crystal pyrophosphate deposition (CPPD) | 0, none; 1, presence of CPPD changes |
Kne pain last week | 0, no pain; 1, some pain; 2, moderate pain; 3, severe pain |
HAND joint osteophytes | 30 joints: 0, none; 1, minor; 2, moderate; 3, major size of osteophytes |
Hand joint synovitis (combined synovitis and effusion) | 30 joints: 0, none; 1, minor; 2, moderate; 3, major |
Hand joint vascularity | 30 joints: 0, none; 1, minor (1-2 small vessels); 2, moderate; 3, major |
Cardiovascular examination | |
Heart rate | Beats per minute |
Systolic blood pressure (monitor) | mmHg |
Diastolic blood pressure (monitor) | mmHg |
Ankle brachial index (ABI) | Systolic blood pressure leg (mmHg)/ Systolic blood pressure arm (mmHg) |
Arterial stiffness | Pulse wave velocity, augmentation index |
ECG | Electrocardiogram |
Surgery/injuries | |
Hip prosthesis | Yes/No; Right/Left; Year of surgery |
Hip surgery/injury | Yes/No; Right/Left; Type surgery/injury; Type treatment; MD/Hospital |
Knee prosthesis | Yes/No; Right/Left; Year of surgery |
Knee surgery/injury | Yes/No; Right/Left; Type surgery/injury; Type treatment; MD/Hospital |
Hand surgery/injury | Yes/No; Right/Left; Type surgery/injury; Type treatment; MD/Hospital |
Hand synovectomy | Yes/No; Number of operations |
Hand joint prosthesis | Yes/No; Number of operations |
Hand joint fusion | Yes/No; Number of operations |
Other operations on hand joints or tendons | Yes/No; Number of operations |
Anthropometric data | |
Body weight | Centimeters |
Body height | Kilograms |
Hip circumference | Centimeters |
Waist circumference | Centimeters |
Digital photo of hands | Standardised photo from above, both hands on top of a black fabric on a small tray |
Biological samples | |
Blood haemoglobin | g/dL |
Blood erythrocyte sedimentation rate (ESR) | mm/h, whole blood and blood serum are stored in a biobank |
Urine | Are stored in a biobank |