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Table 1 Clinical, microbiological, and laboratory data for the 21 patients with prosthetic joint infection

From: Sonication of antibiotic-loaded cement spacers in a two-stage revision protocol for infected joint arthroplasty

Patient No/Age, Y/Sex

Prosthesis

Medical condition

Pre-operative culture/ Microorganism

Pre-op CRP mg/dl

Intra-operative culture (i)

Sonication culture/Prosthesis

Pre-2ndstage CRP mg/dl

Interim Period/ Second stage surgery

Intra-operative culture (ii)

Sonication culture/Spacer

3rdstage surgery/Follow-Up/Final outcome

1/74/M

TKA

none

joint aspiration fluid/PA

1.0

no growth

no growth

1.2

30 days/reimplantation

no growth

no growth

none/28 months/no recurrence

2/65/F

TKA

none

joint aspiration fluid/MSSA

1.8

MSSA

MSSA

1.2

30 days/reimplantation

no growth

MSSA

early debridement/25 months/no recurrence

3/70/M

TKA

none

culture of sinus tract/ PA

2.5

PA

PA

2.1

85 days/arthrodesis

PA

PA

none/23 months/no recurrence/ bony fusion

4/68/M

TKA

none

joint aspiration fluid/CONS

2.8

CONS

CONS

0.4

87 days/reimplantation

no growth

no growth

none/25 months/no recurrence

5/71/F

TKA

none

joint aspiration fluid/no growth

2.3

CONS

CONS

0.3

90 days/reimplantation

no growth

no growth

none/24 months/no recurrence

6/70/M

TKA

none

joint aspiration fluid/no growth

30.0

CONS

CONS

0.2

90 days/reimplantation

no growth

no growth

none/28 months/no recurrence

7/71/M

TKA

none

joint aspiration fluid/no growth

3.1

CONS

CONS

0.3

92 days/reimplantation

no growth

no growth

none/27 months/no recurrence

8/78/M

TKA

none

culture of sinus tract/ PA

3.5

PA

PA

1.0

92 days/ arthrodesis

PA

PA

none/25 months/no recurrence/ fibrous union

9/72/M

TKA

none

joint aspiration fluid/CONS

4.1

CONS

CONS

0.4

95 days/reimplantation

no growth

no growth

none/27 months/no recurrence

10/55/F

THA

none

joint aspiration fluid/no growth

3.5

MSSA

MSSA

0.3

100 days/reimplantation

no growth

MSSA

early debridement/20 months/no recurrence

11/64/M

TKA

none

joint aspiration fluid/MSSA

1.8

MSSA

MSSA

0.3

120 days/reimplantation

no growth

no growth

none/26 months/no recurrence

12/55/F

TKA

diabetes

joint aspiration fluid/no growth

0.3

MSSA

CONS

0.3

120 days/reimplantation

no growth

no growth

none/27 months/no recurrence

13/62/F

THA

diabetes

none

15.0

CONS

CONS

0.3

125 days/reimplantation

no growth

no growth

none/23 months/no recurrence

14/64/F

TKA

none

joint aspiration fluid/no growth

1.9

no growth

no growth

0.3

150 days/reimplantation

no growth

no growth

none/23 months/no recurrence

15/63/M

TKA

none

joint aspiration fluid/MSSA

2.0

MSSA

none

1.7

150 days/reimplantation

no growth

no growth

none/26 months/no recurrence

16/68/M

THA

psoriasis

culture of sinus tract/MRSA

4.4

MRSA

MRSA

0.4

180 days/reimplantation

no growth

MRSA

Girdlestone arthroplasty

18 months/no recurrence

17/58/F

TKA

schizophrenia

culture of sinus tract/ MSSA

0.5

CONS

MSSA

0.7

180 days/arthrodesis

MSSA

MSSA

none/24 months/no recurrence/ bony fusion

18/60/F

THA

none

culture of sinus tract/MSSA

30.0

MSSA

MSSA

0.3

180 days/reimplantation

no growth

no growth

none/26 months/no recurrence

19/66/M

THA

none

none

5.8

CONS

CONS

0.4

180 days/reimplantation

no growth

no growth

none/22 months/no recurrence

20/69/F

TKA

none

joint aspiration fluid/CONS

2.0

CONS

CONS

0.5

210 days/reimplantation

no growth

no growth

none/25 months/no recurrence

21/64/F

TKA

none

joint aspiration fluid/no growth

1.8

no growth

no growth

0.3

240 days/reimplantation

no growth

no growth

none/29 months/no recurrence

  1. Abbreviations: CRP C-reactive protein, TKA total knee arthroplasty, THA total hip arthroplasty, MSSA methicillin-sensible Staphylococcus aureus, MRSA methicillin-resistant Staphylococcus aureus, CONS coagulase-negative Staphylococcus, PA Pseudomonas Aeruginosa.