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Table 1 Age, histological and biochemical findings in patient groups

From: Cartilage collagen damage in hip osteoarthritis similar to that seen in knee osteoarthritis; a case–control study of relationship between collagen, glycosaminoglycan and cartilage swelling

 

Reference (n = 20)

OA (n = 16)

P value

Age (years)

83 (77–85.5)

66.5 (61–75.5)

≤0.001

Mankin grade

2 (1–2)

4 (3.5-5)

≤0.001

Immunostaining score

0.5 (0.5-0.5)

2 (2–3)

≤0.001

ECP

0.45 (0.38-0.63)

1.04 ( 0.84-1.56)

≤0.001

% Hydration

68.1 (64–70.4)

73.6 (70.8-77.9)

≤0.001

GAG

   

Wet

39.8 (34–45.6)

38.6 (34–45.2)

0.644

Dry

128.8 (119.6-135)

152.8 (129.4-165)

0.012

Total hydroxyproline

   

Wet

25.3 (23.1-27.5)

22.4 (18–27.3)

0.083

Dry

79.6(72.2-87)

84.6 (76.4-95.7)

0.233

  1. Reported values are medians (25–75 percentiles). Values of GAG and total hydroxyproline (i.e. total collagen) are expressed as micrograms per milligram wet and dry weight of cartilage tissue. ECP stands for % extractable collagen pool and is expressed as a percentage of the total amount of collagen.