Figure 3

Time course of dynamic gait parameters (A-J) in mice with phosphate buffered saline (PBS) or (K-T) complete Freund’s adjuvant (CFA)-injected intra-articularly in the right hind (RH) limb i.e. stance phase duration (A and K) and ratio of stance phase duration between RH and left hind (LH) limbs (B and L), swing phase duration (C and M) and ratio of swing phase duration between RH and LH limbs (D and N), duty cycle {stance phase duration/(stance + swing phases duration) x 100} (E and O) and ratio of duty cycle between RH and LH limbs (F and P), stride length (G and Q) and ratio of stride length between RH and LH limbs (H and R), swing speed (I and S) and ratio of swing speed between RH and LH limbs (J and T). Each point represents the mean ± S.E.M of the values obtained from 7 (PBS) to 12 (CFA) animals. Statistically significant differences between RH and LH at the same time point post-CFA administration (K, M, O and S). ^* p < 0.05 and ^** p < 0.01 (repeated measures two-way ANOVA followed by Bonferroni post-tests) and in comparison with ratio of RH/LH values before CFA injection (L, N, P and T): ^* p < 0.05 and ^** p < 0.01 (one-way ANOVA followed by Dunnett's Multiple Comparison Test).