Table 1 Baseline demographics and illness characteristics
Older | Younger | Older versus younger | |||
|---|---|---|---|---|---|
Variable | Placebo N=94 | Duloxetine N=103 | Placebo N=154 | Duloxetine N=136 | p values |
Age in years, mean (SD) | 72.0 (4.0) | 71.4 (4.1) | 56.2 (5.7) | 56.0 (5.8) | <.001 |
Female, n (%) | 72 (76.6) | 61 (59.2) | 116 (75.3) | 98 (72.1) | .19 |
Caucasian, n (%) | 88 (93.6) | 97 (94.2) | 136 (88.3) | 123 (90.4) | .11 |
OA duration, years, mean (SD) | 8.1 (8.1) | 7.9 (8.3) | 5.3 (5.5) | 5.5 (6.0) | <.001 |
OA pain, years. mean (SD) | 9.4 (8.1) | 10.3 (9.1) | 7.1 (7.1) | 7.2 (7.2) | <.001 |
BMI (kg/m2), mean (SD) | 30.0 (4.6) | 30.1 (4.1) | 30.9 (4.9) | 29.9 (5.0) | .45 |
Pain diary ratings, mean (SD) | 6.2 (1.4) | 6.0 (1.3) | 6.1 (1.2) | 6.1 (1.2) | .56 |
BPI, mean (SD) | 6.3 (1.5) | 6.0 (1.6) | 6.1 (1.4) | 6.2 (1.4) | .83 |
NSAID use, n (%)a | 39 (41.5) | 37 (35.9) | 73 (47.4) | 68 (50.0) | .03 |