Table 2 In vitro results of hMSC cultured on HDM_derm and CTR for 7 and 14 days
From: Response of human chondrocytes and mesenchymal stromal cells to a decellularized human dermis
HDM_derm | CTR | Two-way ANOVA | |||
|---|---|---|---|---|---|
7 days | 14 days | 7 days | 14 days | ||
CPII (pg/mg) | 82.2 ± 1.5 | 136.8 ± 3.0° | 90.9 ± 4.1 | 140.9 ± 2.6° | F=4.86, p < 0.05 |
Aggrecan (ng/mg) | 191.7 ± 6.1*** | 265.7 ± 7.4***, °°° | 129.7 ± 3.5 | 184.0 ± 5.0°°° | F=24.02, p < 0.0005 |
TGF-β1 (pg/mg) | 926.9 ± 4.5*** | 894.1 ± 18.9*** | 644.2 ± 23.1 | 324.1 ± 75.6°°° | F=37.3, p < 0.0005 |
IL-1β (pg/mg) | 0.5 ± 0.0 | 0.5 ± 0.1 | 0.4 ± 0.0 | 0.6 ± 0.0 | NS |
MMP3 (ng/mg) | 0.01 ± 0.01 | 0.18 ± 0.03 | Not detected | Not detected | NS |