| |
IL18RAP(rs1420106)
|
IL18RAP(rs917997)
|
MMP3(rs72520913)
|
|---|
|
Genotype
|
A/A
|
A/G
|
G/G
|
T/T
|
C/T
|
C/C
|
A/A
|
A/C
|
C/C
|
|---|
|
Number of Patients
|
7
|
33
|
53
|
7
|
36
|
50
|
18
|
56
|
19
|
|
Males / Females
|
2/5
|
10/23
|
23/30
|
2/5
|
11/25
|
22/28
|
8/10
|
19/37
|
8/11
|
|
Age at follow-up
|
49.9 [9.1]
|
49.3 [12.9]
|
53.8 [7.3]
|
49.9 [9.1]
|
49.8 [8.2]
|
53.7 [7.4]
|
51.6 [8.7]
|
53.2 [6.7]
|
48.4 [10.0]
|
|
Mean [SD]
|
|
Fusion/cognitive
|
5/2
|
23/10
|
32/21
|
5/2
|
24/12
|
31/19
|
10/8
|
39/17
|
11/8
|
|
Baseline ODI
|
43.1 [8.9]
|
47.6 [12.9]
|
42.0 [9.6]
|
43.1 [8.9]
|
46.5 [18.2]
|
42.5 [9.6]
|
40.3 [10.0]
|
45.1 [11.0]
|
44.6 [11.8]
|
|
Mean [SD]
|
|
Follow-up ODI
|
41.1 [20.6]
|
23.9 [18.5]
|
21.9 [17.6]
|
41.1 [20.6]
|
25.1 [18.2]
|
21.0 [17.6]
|
25.2 [14.1]
|
24.6 [19.6]
|
21.3 [19.8]
|
|
Mean [SD]
|
|
ODI change
|
- 2 [17.8]
|
- 23.8 [20.8]
|
- 20.0 [20.8]
|
- 2 [17.8]
|
- 21.4 [21.5]
|
- 21.5 [19.6]
|
- 15.2 [16.3]
|
- 20.4 [22.0]
|
- 23.3 [20.8]
|
|
Mean [SD]
|
|
Baseline VAS LBP
|
56.5 [14.2]
|
64.5 [13.3]
|
61.9 [13.7]
|
56.5 [14.2]
|
63.7 [13.1]
|
62.3 [14.0]
|
59.5 [11.7]
|
62.5 [13.5]
|
64.7 [15.9]
|
|
Mean [SD]
|
|
Follow-up VAS LBP
|
48.8 [23.2]
|
38.4 [25.3]
|
36.0 [25.8]
|
48.8 [23.2]
|
39.1 [24.5]
|
35.3 [26.3]
|
48.7 [20.0]
|
33.8 [25.6]
|
39.2 [27.5]
|
|
Mean [SD]
|
|
VAS LBP change
|
- 7.7 [24.3]
|
- 26.1 [25.8]
|
- 25.9 [32.9]
|
- 7.7 [24.3]
|
- 24.6 [25.3]
|
- 27.0 [33.5]
|
- 10.8 [18.5]
|
- 28.7 [33.2]
|
- 25.5 [26.2]
|
|
Mean [SD]
|
- Worst possible score for ODI and VAS LBP was 100.
