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Table 2 Hierarchy of Source Documents

From: Malignancy validation in a United States registry of rheumatoid arthritis patients

Type of Document Level of Confidence* N, % Used**
Biopsy report 1 173 (57.1%)
Oncologist Note 1 58 (19.1%)
Radiation Oncologist Note 1 9 (2.3%)
Dermatologist note (skin cancers only) 1 6 (2%)
OB-GYN Note (for OB-GYN cancers only) 1 1 (0.3%)
Urologist Note (for GU cancers only) 1 2 (0.7%)
Admission note 2 2 (0.7%)
Discharge summary 2 5 (1.7%)
Rheumatologist Note 2 16 (5.3%)
Other Physician Note 2 28 (9.2%)
Pharmaceutical Company adverse event form 3 3 (1.0%)
  1. * For Level 1, sufficient independently to confirm a diagnosis of malignancy
  2. For level 2, if a date of diagnosis (month and year) on the adverse event form or in the note was also provided, and a histology was submitted, defined as a Probable malignancy. If either of that data was absent, defined as a Possible malignancy.
  3. For level 3, if tissue diagnosis included, defined as a Probable malignancy. If not, defined as a Possible malignancy.
  4. ** For cases with multiple source documents, only the document with the highest hierarchical value was used. 303 cases had submitted documents (Total N).