Variables | Data Collection Method | Data Collection Points | |||
---|---|---|---|---|---|
Baseline | 6 months | 12 months | 18 months | ||
Primary outcome measures | Â | Â | Â | Â | Â |
Hip and spine BMD | DXA hip and spine scan | x | Â | x | x |
Functional muscle power | Stair climbing test | x | x | x | x |
Secondary outcome measures | Â | Â | Â | Â | Â |
Muscle power | Leg press (3-RM) | x | x | x | x |
 | 30 second sit-to-stand | x | x | x | x |
Muscle strength | Leg press and lat pulldown (3-RM) | x | x | x | x |
Muscle function and balance | Functional reach test | x | x | x | x |
 | Four-square step test | x | x | x | x |
 | Timed-up-and-go (TUG) | x | x | x | x |
Anthropometry and body composition | Height and weight | x | x | x | x |
 | DXA lean mass and fat mass | x |  | x | x |
Trabecular bone microarchitecture | MRI knee | x | Â | Â | x |
Falls | Monthly falls calendars | Monthly calendar | |||
Adverse events | Monthly falls calendars | Monthly calendar | |||
Cost effectiveness | EuroQol (EQ-5D) | x | x | x | x |
Quality of life | SF36 questionnaire | x | x | x | x |
Other measures | Â | Â | Â | Â | Â |
Diet | 24-h food recall questionnaire | x | x | x | x |
Lifestyle and medical history | Questionnaire | x | x | x | x |
Biochemistry and hormonal | Serum 25-hydroxyvitaminD | Â | Â | Â | Â |
 |  | x | x | x | x |
 | Parathyroid hormone (PTH) | x |  | x | x |
 | Routine biochemistry | x |  | x | x |
Physical activity | CHAMPS questionnaire | x | x | x | x |
Historical physical activity | Questionnaire | x | Â | Â | Â |
Osteoporosis health beliefs and knowledge | Osteoporosis Knowledge Test (OKT) | x | Â | x | x |
Osteoporosis attitudes and prevention behaviours | Osteoporosis Health Belief Scale (OHBS) | x | Â | x | x |