Figure 5

Glycosaminoglycan production from cells of in vitro maintained and of in vivo implanted hydrogels. Note that most of the glycosaminoglycans (GAG) from the in vitro cultures were found in the culture medium (middle bar). Mean values (n = 6) and standard deviation are shown. In vitro gel: GAG content of the in vitro cultured hydrogel; in vitro gel + medium: GAG content of the in vitro cultured hydrogel plus the GAG released into the combined medium supernatant from two weeks of culture; in vivo: GAG content of the in vivo implanted hydrogel. Statistic: paired t-test comparing the in vitro group (gel + medium) and the in vivo group, * = p < 0.05.