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Table 2 OA score; semi-quantitative method

From: Human telomerase reverse transcriptase and glucose-regulated protein 78 increase the life span of articular chondrocytes and their repair potential

Grade (key feature) Stage % Involvement (surface, area, volume)  
  Stage 1 < 10% Stage 2 10-25% Stage 3 25-50% Stage 4 > 50%
Grade 1(surface
intact)
1 2 3 4
Grade 2 (surface
discontinuity)
2 4 6 8
Grade 3 (vertical
fissures, clefts)
3 6 9 12
Grade 4 (erosion) 4 8 12 16
Grade 5(denudation) 5 10 15 20
Grade 6(deformation) 6 12 18 24
  1. Score = grade × stage