Local treatment of a bone graft by soaking in zoledronic acid inhibits bone resorption and bone formation. A bone chamber study in rats

Table 6 Bone Volume/Total Volume (BV/TV)

Group	1. Saline control	2. Short soaking time	3. Long soaking time	4. Topical zoledronic acid, no rinse	5. Zoledronic acid systemic injection
1. Saline control	-	-	-	-	-
2. Short soaking time	<0.001	-	-	-	-
3. Long soaking time	<0.001	1	-	-	-
4. Topical zoledronic acid, no rinse	<0.001	0.082	0.022	-	-
5. Zoledronic acid systemic injection	0.001	0.002	0.001	0.01	-

P values for comparisons of BV/TV between treatment groups. Bold numbers indicate p < 0.05.

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