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Table 4 Area Under Curve (AUC) of Receiver Operating Characteristics (ROC)

From: FRAX® tool, the WHO algorithm to predict osteoporotic fractures: the first analysis of its discriminative and predictive ability in the Spanish FRIDEX cohort

   AUC ROC CI 95% p - value
AUC ROC 10-year prediction of MAJOR FRACTURE BMD with FN T-score 0.661 (0.583-0.739) p<0.001
BMD with L1-L4 T-score 0.638 (0.565-0.711) p<0.001
FRAX® tool without BMD 0.693 (0.622-0.763) p<0.001
FRAX® tool with FN T-score 0.716 (0.646-0.786) p<0.001
FRAX® tool with spine L1-L4 T-score 0.712 (0.644-0.780) p<0.001
AUC ROC 10-year prediction of HIP FRACTURE BMD with FN T-score 0.779 (0.631-0.929) p<0.001
BMD with L1-L4 T-score 0.630 (0.487-0.773) (ns)
FRAX® tool without BMD 0.888 (0.824-0.952) p<0.001
FRAX® tool with FN T-score 0.849 (0.737-0.962) p<0.001
  FRAX® tool with spine L1-L4 T-score 0.767 (0.658-0.876) p<0.001
  1. AUC ROC: Area Under Curve of Receiver Operating Characteristics; BMD: Bone Mineral Density; FN: Femoral Neck; L1-L4: Lumbar Spine; CI: Confidence Interval; ns: Not significant.