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Table 4 Area Under Curve (AUC) of Receiver Operating Characteristics (ROC)

From: FRAX® tool, the WHO algorithm to predict osteoporotic fractures: the first analysis of its discriminative and predictive ability in the Spanish FRIDEX cohort

  

AUC ROC

CI 95%

p - value

AUC ROC 10-year prediction of MAJOR FRACTURE

BMD with FN T-score

0.661

(0.583-0.739)

p<0.001

BMD with L1-L4 T-score

0.638

(0.565-0.711)

p<0.001

FRAX® tool without BMD

0.693

(0.622-0.763)

p<0.001

FRAX® tool with FN T-score

0.716

(0.646-0.786)

p<0.001

FRAX® tool with spine L1-L4 T-score

0.712

(0.644-0.780)

p<0.001

AUC ROC 10-year prediction of HIP FRACTURE

BMD with FN T-score

0.779

(0.631-0.929)

p<0.001

BMD with L1-L4 T-score

0.630

(0.487-0.773)

(ns)

FRAX® tool without BMD

0.888

(0.824-0.952)

p<0.001

FRAX® tool with FN T-score

0.849

(0.737-0.962)

p<0.001

 

FRAX® tool with spine L1-L4 T-score

0.767

(0.658-0.876)

p<0.001

  1. AUC ROC: Area Under Curve of Receiver Operating Characteristics; BMD: Bone Mineral Density; FN: Femoral Neck; L1-L4: Lumbar Spine; CI: Confidence Interval; ns: Not significant.