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Table 2 Baseline risk factors and falls in previous year for major fracture

From: FRAX® tool, the WHO algorithm to predict osteoporotic fractures: the first analysis of its discriminative and predictive ability in the Spanish FRIDEX cohort

 

65 Women with fracture

705 Women without fracture

P- value

CI 95%

RR

CI 95% RR

Age (SD)

61.2 (9.7)

56.4 (7.7)

<0.001

2.4-7.3

2.62 (*)

(1.63 – 4.21)

Weight (SD)

67.4 (11.5)

66.6 (11.4)

0.559

ns

-

-

Height (SD)

155.3 (6.1)

155.1 (5.8)

0.805

ns

-

-

BMI (SD)

28.0 (4.4)

27.7 (4.7)

0.653

ns

1.19 (**)

(0.31 – 4.53)

Previous Fracture (%)

43.1

18.6

<0.001

12.1-36.9

2.91

(1.84 – 4.60)

Parental Hip Fracture (%)

15.4

15.6

0.963

ns

0.98

(0.52 – 1.88)

Smoker (%)

9.2

11.3

0.604

ns

0.81

(0.36 – 1.82)

Alcohol Risk (%)

1.5

1

0.508

ns

1.49

(0.23 – 9.45)

Glucocorticoids (%)

7.7

2.8

0.052

ns

1.15

(0.94 – 1.40)

Rheumatoid Arthritis (%)

4.6

0.7

0.024

1.2-9.0

4.61

(1.83 – 11.63)

Falls in previous year (%)

32.3

22.3

0.066

ns

1.59

(0.97 – 2.60)

Osteoporosis (baseline DXA) (%)

50.8

25.8

<0.001

12.4-37.6

4.96 (‡)

(1.98 – 12.43)

Osteopenia (baseline DXA) (%)

41.5

50.9

0.147

ns

2.36 (Φ)

(0.93 – 6.03)

Normal (baseline DXA) (%)

7.7

23.3

0.004

8.4-22.8

-

-

  1. RR: Relative Risk.
  2. (*) < 65 vs. ≥ 65 years.
  3. (**) < 20 vs. ≥ 20.
  4. (‡) Osteoporosis vs. normal.
  5. (Φ) Osteopenia vs. normal.