Table 3 Comparison of AS subjects with respect to disease activity
Active patients(BASDAI ≥ 4; n= 38) | Inactive patients(BASDAI < 4; n= 17) | p value | |
|---|---|---|---|
IL-6 (pg/mL) | 20 (6–545) | 15 (5–277) | 0.2 |
IFNγ (pg/mL) | 0.002 (0.002–1.96) | 0.002 (0.002–0.89) | 0.7 |
BAP (U/L) | 28 (13–107) | 30 (15–49) | 0.3 |
Vitamin D (nM) | 89 (4–266) | 77 (12–240) | 0.6 |
NTX (nM, bone collagen equivalent) | 87 (56–131) | 81 (52–188) | 0.7 |
TRAP 5 (U/L) | 3.7 (2.2–5.8) | 3.9 (2.4–6.6) | 0.4 |
hPTH (pg/mL) | 46 (44–170) | 77 (45–130) | 0.08 |
sRANKL (pmol/L) | 264 (101–956) | 350 (158–1598) | 0.2 |
OPG (pg/mL) | 367 (52–1118) | 274 (71–592) | 0.004 |
sRANKL/OPG | 0.79 (0.14–4.5) | 1.16 (0.4–22.6) | 0.02 |
Sclerostin (pmol/L) | 70 (49–126) | 75 (48–123) | 0.7 |
sFRP1 (ng/mL) | 0.15 (0.1–17) | 0.1 (0.1–0.2) | 0.5 |
DKK1 (pg/mL) | 93 (26–370) | 130 (17–771) | 0.5 |
BASRI-hip | 0 (0–4) | 0.5 (0–4) | 0.2 |
BASRI-spine | 5.5 (2–12) | 7 (2–12) | 0.3 |
BASMI | 4 (1–9) | 2.5 (1–9) | 0.7 |
BMD-Lumbar spine (g/cm2) | 0.9 (0.7–1.4) | 0.9 (0.7–1.6) | 0.8 |
BMD-Femoral neck (g/cm2) | 0.7 (0.6–1.1) | 0.8 (0.5–1) | 0.9 |