miRNA name | Sanger Accession | Fold Change | p value |
---|
hsa-miR-483-5p | MIMAT0004761 | 2.44 | 2.35×10-4
|
hsa-miR-149* | MIMAT0000450 | −1.76 | 2.28×10-3
|
hsa-miR-582-3p | MIMAT0004797 | −1.94 | 3.31×10-4
|
hsa-miR-1227 | MIMAT0005580 | −1.80 | 2.54×10-5
|
hsa-miR-634 | MIMAT0003304 | −1.75 | 7.66×10-4
|
hsa-miR-576-5p | MIMAT0003241 | −4.74 | 6.68×10-4
|
hsa-miR-641 | MIMAT0003311 | −2.36 | 1.71×10-3
|
- Data from microarray analysis of miR expression was used to identify miRNAs with differential expression in normal versus OA micropellets. Only miRNAs with a statistically significant (p value < 0.1) differential expression and a fold-change cut-off >1.5 are listed. U Mann–Whitney test without Benjamin-Hochberg multiple testing corrections were used to compute p values. Fold change gives the absolute ratio of normalized intensities (no log scale) between the average intensities of the samples grouped (N versus OA). Positive fold change values indicate elevated expression in OA micropellets, whilst negative fold change values indicate elevated expression in normal micropellets.