Expression profile analysis of mycotoxin-related genes in cartilage with endemic osteochondropathy kashin-beck disease

Table 3 Differently expressed gene ontology between KBD cartilage and healthy cartilage

Gene Ontology Category	Function	NES^a	P-value
APOPTOSIS_GO	Apoptosis	0.450	0.032
REGULATION_OF_APOPTOSIS	Apoptosis	0.470	0.032
REGULATION_OF_PROGRAMMED_CELL_DEATH	Apoptosis	0.470	0.032
ANTI_APOPTOSIS	Apoptosis	0.551	<0.001
ORGAN_DEVELOPMENT	Development	0.511	<0.001
SYSTEM_DEVELOPMENT	Development	0.512	<0.001
REGULATION_OF_DEVELOPMENTAL_PROCESS	Development	0.473	0.050
ORGAN_MORPHOGENESIS	Development	0.663	<0.001
ANATOMICAL_STRUCTURE_DEVELOPMENT	Development	0.506	<0.001

^a denotes normalized enrichment score (NES) calculated by GSEA. Positive NES indicate gene ontology up-regulated in KBD cartilage compared to healthy cartilage.

ISSN: 1471-2474