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Table 1 Histological analysis of L-6r mAb treated and control (Kh-5) treated mdx and bl/10 mice

From: IL-6 signaling blockade increases inflammation but does not affect muscle function in the mdx mouse

  Regenerating fibers (n) Diameter (um) Central nucleated fibers (%) Gas Central nucleated fibers (%) Dia Inflamation score
Kh5-mdx 5.6 ± 1.2 34.1 ± 1.0 72.8 ± 2.6 32.8 ± 1.9 14.9 ± 3.4
IL6rab-mdx 9.6 ± 1.7 31.7 ± 1.6 64.5 ± 6.9 29.3 ± 1.4 26.2 ± 3.1
kh5-bI/10 0.4 ± 0.1 38.2 ± 1.1 2.2 ± 0.5 1.8 ± 0.3 1.4 ± 1.2
IL6Ab-bl/10 0.2 ± 0.1 40.1 ± 0.8 1.5 + 0.5 0.9 ± 0.1 3.1 ± 1.1
  1. Data are means and SEM for the gastrocnemius (Gas) unless indicated as diaphragm (Dia).