Figure 6
From: IL-6 signaling blockade increases inflammation but does not affect muscle function in the mdx mouse
Gene expression of mdx treated relative to control-Ab treated liver. Insulin like growth factor 1 (IGF1) and serum amyloid A (SAA) were measured in liver samples of mdx mice treated with IL-6r mAb (blocks IL-6 signaling) or control Ab. Samples are normalized to GAPDH and the fold change from mdx control mice is presented. Independent t-tests examined statistical differences (* indicates p < 0.05). Data are means and bars represent SEM.